UniProt O66465
Phospho-N-acetylmuramoyl-pentapeptide-transferase (O66465)
Phospho-N-acetylmuramoyl-pentapeptide-transferase (UniProt O66465), EC 2.7.8.13: 12 experimental structures on GenesisL1, 6 ligands bound, 65 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O66465
- Protein
- Phospho-N-acetylmuramoyl-pentapeptide-transferase
- EC
- 2.7.8.13
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 65 · 5 records with a druggable one
Structures
12 records of O66465 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4J72 | Crystal Structure of polyprenyl-phosphate N-acetyl hexosamine 1-phosphate transferase | x-ray diffraction | A, B | — | — |
| 4J72 | Crystal structure of polyprenyl-phosphate N-acetyl hexosamine 1- phosphate transferase | x-ray diffraction | A, B | — | — |
| 5CKR | Crystal Structure of MraY in complex with Muraymycin D2 | x-ray diffraction | A | 57M | 3 (best 0.58) |
| 5CKR | Crystal structure of mray in complex with muraymycin D2 | x-ray diffraction | A | — | — |
| 6OYH | Crystal structure of MraY bound to carbacaprazamycin | x-ray diffraction | A, C, B, D | NK4 | 20 (best 0.83) |
| 6OYH | Crystal structure of mray bound to carbacaprazamycin | x-ray diffraction | A, C, B, D | NK4 | — |
| 6OYZ | Crystal structure of MraY bound to capuramycin | x-ray diffraction | A, C, B, D | NKM | 20 (best 0.83) |
| 6OYZ | Crystal structure of mray bound to capuramycin | x-ray diffraction | A, C, B, D | NKM | — |
| 6OZ6 | Crystal structure of mray bound to 3'-hydroxymureidomycin a | x-ray diffraction | A, B, C, D | NKD | — |
| 9B70 | Cryo-EM structure of MraY in complex with analogue 2 | electron microscopy | B, A | A1AI1 | 11 (best 0.82) |
| 9B71 | Cryo-EM structure of MraY in complex with analogue 3 | electron microscopy | A, B | A1AI2 | 11 (best 0.82) |
| O66465 | AlphaFold monomer V2.0 prediction for phospho-N-acetylmuramoyl- pentapeptide-transferase (O66465) | — | — | — |
Ligands
- NK4 · (5S)-5'-O-(5-amino-5-deoxy-beta-D-ribofuranosyl)-5'-C-[(2S,5S,6S)-5-carboxy-6-heptadecyl-1,4-dimethyl-3-oxo-1,4-diazepan-2-yl]uridine · in 2 records
- NKM · (2~{S},3~{S},4~{S})-2-[(1~{R})-2-azanyl-1-[(2~{S}, 3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-methoxy-4-oxidanyl-oxolan-2-yl]-2-oxidanylidene-ethoxy]-3,4-bis(oxidanyl)-~{N}-[(3~{S})-2-oxidanylideneazepan-3-yl]-3,4-dihydro-2~{H}-pyran-6-carboxamide · in 2 records
- 57M · Muraymycin D2 · in 1 record
- A1AI1 · (2~{S},3~{S})-3-[(2~{S},3~{R},4~{S},5~{R})-5-(aminomethyl)-3,4-bis(oxidanyl)oxolan-2-yl]oxy-2-[[3-[[[(2~{S})-6-azanyl-2-(hexadecanoylamino)hexanoyl]amino]methyl]phenyl]methylamino]-3-[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]propanoic acid · in 1 record
- A1AI2 · (2~{S},3~{S})-3-[(2~{S},3~{R},4~{S},5~{R})-5-(aminomethyl)-3,4-bis(oxidanyl)oxolan-2-yl]oxy-3-[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]-2-[[4-[[[(2~{S})-5-carbamimidamido-2-(hexadecanoylamino)pentanoyl]amino]methyl]phenyl]methylamino]propanoic acid · in 1 record
- NKD · (2~{S})-2-[[(2~{S})-1-[[(2~{S},3~{S})-3-[[(2~{S})-2-azanyl-3-(3-hydroxyphenyl)propanoyl]-methyl-amino]-1-[[(~{Z})-[(3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl) oxolan-2-ylidene]methyl]amino]-1-oxidanylidene-butan-2-yl]amino]-4-methylsulfanyl-1-oxidanylidene-butan-2-yl]carbamoylamino]-3-(3-hydroxyphenyl)propanoic acid · in 1 record
Elsewhere
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