UniProt O60927
E3 ubiquitin-protein ligase PPP1R11 (O60927)
E3 ubiquitin-protein ligase PPP1R11 (UniProt O60927), EC 2.3.2.27: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O60927
- Protein
- E3 ubiquitin-protein ligase PPP1R11
- EC
- 2.3.2.27
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 1 record with a druggable one
Structures
3 records of O60927 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8DWK | Inhibitor-3:PP1 reconstituted complex | x-ray diffraction | C, D | — | — |
| 8U5G | Crystal structure of the co-expressed SDS22:PP1:I3 complex | x-ray diffraction | C | FE, PO4 | 2 (best 0.61) |
| O60927 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase PPP1R11 (O60927) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8DWK chain C against the predicted model O60927: TM-score 0.35, RMSD 2.04 Å
- 8DWK chain D against the predicted model O60927: TM-score 0.34, RMSD 1.84 Å
- 8U5G chain C against the predicted model O60927: TM-score 0.33, RMSD 1.93 Å
Elsewhere
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