UniProt O60921
Checkpoint protein HUS1 (O60921)
Checkpoint protein HUS1 (UniProt O60921): 12 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60921
- Protein
- Checkpoint protein HUS1
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 14 · 4 records with a druggable one
Structures
13 records of O60921 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3A1J | Crystal structure of the human Rad9-Hus1-Rad1 complex | x-ray diffraction | B | — | — |
| 3A1J | Crystal structure of the human RAD9-HUS1-RAD1 complex | x-ray diffraction | B | — | — |
| 3G65 | Crystal Structure of the Human Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex | x-ray diffraction | C | — | — |
| 3G65 | Crystal structure of the human RAD9-RAD1-HUS1 DNA damage checkpoint complex | x-ray diffraction | C | — | — |
| 3GGR | Crystal Structure of the Human Rad9-Hus1-Rad1 complex | x-ray diffraction | B | — | — |
| 3GGR | Crystal structure of the human RAD9-HUS1-RAD1 complex | x-ray diffraction | B | — | — |
| 6J8Y | Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex | x-ray diffraction | B | — | 4 (best 0.59) |
| 6J8Y | Crystal structure of the human RAD9-HUS1-RAD1-rhino complex | x-ray diffraction | B | — | — |
| 7Z6H | Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp | electron microscopy | C | — | 1 (best 0.62) |
| 7Z6H | Structure of DNA-bound human RAD17-rfc clamp loader and 9-1-1 checkpoint clamp | electron microscopy | C | — | — |
| 8GNN | Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex | x-ray diffraction | B | — | 3 (best 0.69) |
| 8WU8 | Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex | x-ray diffraction | B | — | 3 (best 0.40) |
| O60921 | AlphaFold monomer V2.0 prediction for checkpoint protein HUS1 (O60921) | predicted | A | — | 3 (best 0.67) |
Experiment against prediction
- 3G65 chain C against the predicted model O60921: TM-score 0.99, RMSD 0.71 Å
- 3G65 chain C against the predicted model O60921: TM-score 0.99, RMSD 0.71 Å
- 3A1J chain B against the predicted model O60921: TM-score 0.98, RMSD 0.83 Å
- 3A1J chain B against the predicted model O60921: TM-score 0.98, RMSD 0.83 Å
- 8WU8 chain B against the predicted model O60921: TM-score 0.98, RMSD 0.85 Å
- 8GNN chain B against the predicted model O60921: TM-score 0.97, RMSD 0.77 Å
- 6J8Y chain B against the predicted model O60921: TM-score 0.97, RMSD 0.90 Å
- 6J8Y chain B against the predicted model O60921: TM-score 0.97, RMSD 0.90 Å
- 7Z6H chain C against the predicted model O60921: TM-score 0.97, RMSD 1.14 Å
- 7Z6H chain C against the predicted model O60921: TM-score 0.97, RMSD 1.14 Å
Elsewhere
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