UniProt O60667
Fas apoptotic inhibitory molecule 3 (O60667)
Fas apoptotic inhibitory molecule 3 (UniProt O60667): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60667
- Protein
- Fas apoptotic inhibitory molecule 3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 28 · 5 records with a druggable one
Structures
7 records of O60667 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YSG | Cryo-EM structure of human FcmR bound to sIgM | electron microscopy | R, S, U, V | — | — |
| 7YTC | Cryo-EM structure of human FcmR bound to IgM-Fc/J | electron microscopy | R | — | 3 (best 0.87) |
| 7YTD | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | electron microscopy | R, S, U, V | — | 9 (best 0.85) |
| 8BPE | 8:1 binding of FcMR on IgM pentameric core | electron microscopy | M, P, O, R, N, Q, S, I | NAG | 11 (best 0.86) |
| 8BPF | FcMR binding at subunit Fcu1 of IgM pentamer | electron microscopy | I | — | 2 (best 0.87) |
| 8BPG | FcMR binding at subunit Fcu3 of IgM pentamer | electron microscopy | B, A | NAG | 3 (best 0.80) |
| O60667 | AlphaFold monomer V2.0 prediction for fas apoptotic inhibitory molecule 3 (O60667) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 8BPE chain P against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPE chain N against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPE chain M against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPG chain B against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPG chain A against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPE chain S against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPE chain Q against the predicted model O60667: TM-score 0.94, RMSD 1.05 Å
- 8BPE chain O against the predicted model O60667: TM-score 0.94, RMSD 1.06 Å
- 8BPE chain R against the predicted model O60667: TM-score 0.94, RMSD 1.07 Å
- 7YSG chain S against the predicted model O60667: TM-score 0.92, RMSD 1.02 Å
Elsewhere
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