UniProt O60609
GDNF family receptor alpha-3 (O60609)
GDNF family receptor alpha-3 (UniProt O60609): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60609
- Protein
- GDNF family receptor alpha-3
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 13 · 1 record with a druggable one
Structures
5 records of O60609 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GH0 | Growth factor/receptor complex | x-ray diffraction | A, B | — | — |
| 2GH0 | Growth FACTOR/RECEPTOR complex | x-ray diffraction | A, B | — | — |
| 6Q2S | Cryo-EM structure of RET/GFRa3/ARTN extracellular complex. The 3D refinement was applied with C2… | electron microscopy | C, D | NAG | 13 (best 0.81) |
| 6Q2S | Cryo-EM structure of RET/GFRA3/ARTN extracellular complex. the 3D refinement was applied with C2… | electron microscopy | C, D | NAG | — |
| O60609 | AlphaFold monomer V2.0 prediction for gdnf family receptor alpha-3 (O60609) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 2GH0 chain B against the predicted model O60609: TM-score 0.99, RMSD 0.50 Å
- 2GH0 chain B against the predicted model O60609: TM-score 0.99, RMSD 0.50 Å
- 6Q2S chain C against the predicted model O60609: TM-score 0.99, RMSD 0.59 Å
- 6Q2S chain C against the predicted model O60609: TM-score 0.99, RMSD 0.59 Å
- 6Q2S chain D against the predicted model O60609: TM-score 0.99, RMSD 0.59 Å
- 6Q2S chain D against the predicted model O60609: TM-score 0.99, RMSD 0.59 Å
- 2GH0 chain A against the predicted model O60609: TM-score 0.99, RMSD 0.62 Å
- 2GH0 chain A against the predicted model O60609: TM-score 0.99, RMSD 0.62 Å
Elsewhere
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