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UniProt O60603

Toll-like receptor 2,Variable lymphocyte receptor B (O60603)

Toll-like receptor 2,Variable lymphocyte receptor B (UniProt O60603): 14 experimental structures on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
O60603
Protein
Toll-like receptor 2,Variable lymphocyte receptor B
Experimental structures
14
Predicted models
0
Ligands
2
Pockets
17 · 1 record with a druggable one

Structures

14 records of O60603 in the MolNFT archive: 14 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1FYWCrystal structure of the tir domain of human TLR2x-ray diffractionA——
1FYWCrystal structure of the tir domain of human TLR2x-ray diffractionA——
1FYXCrystal structure of P681H mutant of tir domain of human TLR2x-ray diffractionA——
1FYXCrystal structure of P681H mutant of tir domain of human TLR2x-ray diffractionA——
1O77Crystal structure of the C713S mutant of the tir domain of human TLR2x-ray diffractionA, B, C, D, E——
1O77Crystal structure of the C713S mutant of the tir domain of human TLR2x-ray diffractionA, B, C, D, E——
2Z7XCrystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptidex-ray diffractionA——
2Z7XCrystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptidex-ray diffractionA——
2Z80Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptidex-ray diffractionA, B——
2Z80Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptidex-ray diffractionA, B——
6NIGCrystal structure of the human TLR2-Diprovocim complexx-ray diffractionA, B, C, DNAG, KQD17 (best 0.86)
6NIGCrystal structure of the human TLR2-diprovocim complexx-ray diffractionA, B, C, DNAG, KQD—
8AR0Solution structure of TLR2 transmembrane and cytoplasmic juxtamembrane regionssolution nmrA——
O60603AlphaFold monomer V2.0 prediction for toll-like receptor 2 (O60603)———

Ligands

  • KQD · (3S,4S,3'S,4'S)-1,1'-(1,4-phenylenedicarbonyl)bis{n~3~, N~4~-bis[(1s,2r)-2-phenylcyclopropyl]pyrrolidine-3,4-dicarboxami de} · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records

Elsewhere

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