UniProt O60565
Gremlin-1 (O60565)
Gremlin-1 (UniProt O60565): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60565
- Protein
- Gremlin-1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
4 records of O60565 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5AEJ | Crystal structure of human Gremlin-1 | x-ray diffraction | A, B, C, D | SO4 | 5 (best 0.76) |
| 5AEJ | Crystal structure of human gremlin-1 | x-ray diffraction | A, B, C, D | — | — |
| 8B7H | Crystal structure of human Gremlin-1 in complex with Fab | x-ray diffraction | A | — | 3 (best 0.39) |
| O60565 | AlphaFold monomer V2.0 prediction for gremlin-1 (O60565) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 8B7H chain A against the predicted model O60565: TM-score 0.89, RMSD 1.22 Å
- 5AEJ chain B against the predicted model O60565: TM-score 0.79, RMSD 2.21 Å
- 5AEJ chain B against the predicted model O60565: TM-score 0.79, RMSD 2.21 Å
- 5AEJ chain C against the predicted model O60565: TM-score 0.79, RMSD 2.13 Å
- 5AEJ chain A against the predicted model O60565: TM-score 0.77, RMSD 2.41 Å
- 5AEJ chain A against the predicted model O60565: TM-score 0.77, RMSD 2.41 Å
- 5AEJ chain D against the predicted model O60565: TM-score 0.75, RMSD 2.50 Å
Elsewhere
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