UniProt O60343
TBC1 domain family member 4 (O60343)
TBC1 domain family member 4 (UniProt O60343): 4 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60343
- Protein
- TBC1 domain family member 4
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
5 records of O60343 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QYB | X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain | x-ray diffraction | A | — | — |
| 3QYB | X-ray crystal structure of human TBC1D4 (AS160) rabgap domain | x-ray diffraction | A | — | — |
| 7NIX | 14-3-3 sigma with AS160 binding site pT642 | x-ray diffraction | B | — | 1 (best 0.54) |
| 7NIX | 14-3-3 sigma with AS160 binding site PT642 | x-ray diffraction | B | — | — |
| O60343 | AlphaFold monomer V2.0 prediction for TBC1 domain family member 4 (O60343) | predicted | A | — | 10 (best 0.52) |
Experiment against prediction
- 3QYB chain A against the predicted model O60343: TM-score 0.99, RMSD 0.74 Å
- 3QYB chain A against the predicted model O60343: TM-score 0.99, RMSD 0.74 Å
- 7NIX chain B against the predicted model O60343: TM-score 0.33, RMSD 1.81 Å
- 7NIX chain B against the predicted model O60343: TM-score 0.33, RMSD 1.81 Å
Elsewhere
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