UniProt O60104
Mediator of RNA polymerase II transcription subunit 7 (O60104)
Mediator of RNA polymerase II transcription subunit 7 (UniProt O60104): 6 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60104
- Protein
- Mediator of RNA polymerase II transcription subunit 7
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
7 records of O60104 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5N9J | Core Mediator of transcriptional regulation | x-ray diffraction | E | — | — |
| 5N9J | Core mediator of transcriptional regulation | x-ray diffraction | E | — | — |
| 5U0P | Cryo-EM structure of the transcriptional Mediator | electron microscopy | G | — | 3 (best 0.80) |
| 5U0P | Cryo-EM structure of the transcriptional mediator | electron microscopy | G | — | — |
| 5U0S | Cryo-EM structure of the Mediator-RNAPII complex | electron microscopy | G | — | — |
| 5U0S | Cryo-EM structure of the mediator-rnapii complex | electron microscopy | G | — | — |
| O60104 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 7 (O60104) | predicted | A | — | 2 (best 0.51) |
Experiment against prediction
- 5U0P chain G against the predicted model O60104: TM-score 0.63, RMSD 3.60 Å
- 5U0P chain G against the predicted model O60104: TM-score 0.63, RMSD 3.60 Å
- 5U0S chain G against the predicted model O60104: TM-score 0.63, RMSD 3.46 Å
- 5U0S chain G against the predicted model O60104: TM-score 0.63, RMSD 3.46 Å
- 5N9J chain E against the predicted model O60104: TM-score 0.60, RMSD 4.24 Å
- 5N9J chain E against the predicted model O60104: TM-score 0.60, RMSD 4.24 Å
Elsewhere
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