UniProt O60015
Ubiquitin-conjugating enzyme E2-21 kDa (O60015)
Ubiquitin-conjugating enzyme E2-21 kDa (UniProt O60015), EC 2.3.2.23: 4 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60015
- Protein
- Ubiquitin-conjugating enzyme E2-21 kDa
- EC
- 2.3.2.23
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
5 records of O60015 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NKZ | Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble… | x-ray diffraction | A, B | — | 8 (best 0.75) |
| 5NKZ | Crystal structure of H. polymorpha ubiquitin conjugating enzyme PEX4P in complex with soluble… | x-ray diffraction | A, B | — | — |
| 5NL8 | Pex4 of Hansenula Polymorpha | x-ray diffraction | A | — | — |
| 5NL8 | PEX4 of hansenula polymorpha | x-ray diffraction | A | — | — |
| O60015 | AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2-21 kda (O60015) | predicted | A | — | 1 (best 0.26) |
Experiment against prediction
- 5NKZ chain A against the predicted model O60015: TM-score 0.98, RMSD 0.74 Å
- 5NKZ chain A against the predicted model O60015: TM-score 0.98, RMSD 0.74 Å
- 5NL8 chain A against the predicted model O60015: TM-score 0.95, RMSD 1.40 Å
- 5NL8 chain A against the predicted model O60015: TM-score 0.95, RMSD 1.40 Å
Elsewhere
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