UniProt O59702
Histone deacetylase clr6 (O59702)
Histone deacetylase clr6 (UniProt O59702), EC 3.5.1.98: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O59702
- Protein
- Histone deacetylase clr6
- EC
- 3.5.1.98
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 29 · 3 records with a druggable one
Structures
4 records of O59702 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8I02 | Cryo-EM structure of the SIN3S complex from S. pombe | electron microscopy | B | ZN, K | 10 (best 0.74) |
| 8I03 | Cryo-EM structure of the SIN3L complex from S. pombe | electron microscopy | C, D | ZN, K | 11 (best 0.86) |
| 8IFG | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | electron microscopy | C | ZN | 8 (best 0.74) |
| O59702 | AlphaFold monomer V2.0 prediction for histone deacetylase CLR6 (O59702) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8I03 chain D against the predicted model O59702: TM-score 0.99, RMSD 0.74 Å
- 8I03 chain C against the predicted model O59702: TM-score 0.98, RMSD 0.84 Å
- 8IFG chain C against the predicted model O59702: TM-score 0.98, RMSD 0.83 Å
- 8I02 chain B against the predicted model O59702: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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