UniProt O53512
Phospho-2-dehydro-3-deoxyheptonate aldolase AroG (O53512)
Phospho-2-dehydro-3-deoxyheptonate aldolase AroG (UniProt O53512), EC 2.5.1.54: 28 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 30 pockets. Binding sites, druggability and experiment against…
- UniProt
- O53512
- Protein
- Phospho-2-dehydro-3-deoxyheptonate aldolase AroG
- EC
- 2.5.1.54
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 30 · 2 records with a druggable one
Structures
29 records of O53512 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B7O | The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium… | x-ray diffraction | A, B | — | — |
| 2B7O | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 2W19 | Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis | x-ray diffraction | A, B | — | — |
| 2W19 | Non-covalent complex between dahp synthase and chorismate mutase from mycobacterium tuberculosis | x-ray diffraction | A, B | — | — |
| 2W1A | Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis… | x-ray diffraction | A, B | — | — |
| 2W1A | Non-covalent complex between dahp synthase and chorismate mutase from mycobacterium tuberculosis… | x-ray diffraction | A, B | — | — |
| 2YPO | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with phenylalanine bound in only one site | x-ray diffraction | A, B | — | — |
| 2YPO | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with phenylalanine bound in only one site | x-ray diffraction | A, B | — | — |
| 2YPP | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules | x-ray diffraction | A, B | — | — |
| 2YPP | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules | x-ray diffraction | A, B | — | — |
| 2YPQ | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound | x-ray diffraction | A, B | — | — |
| 2YPQ | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound | x-ray diffraction | A, B | — | — |
| 3KGF | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium… | x-ray diffraction | A, B | — | — |
| 3KGF | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 3NUD | The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 3NUD | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 3NUE | The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 3NUE | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 3NV8 | The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol… | x-ray diffraction | A, B | — | — |
| 3NV8 | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol… | x-ray diffraction | A, B | — | — |
| 3PFP | Structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis… | x-ray diffraction | A, B | — | — |
| 3PFP | Structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis… | x-ray diffraction | A, B | — | — |
| 3RZI | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 3RZI | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium… | x-ray diffraction | A, B | — | — |
| 5CKV | DAHP synthase from Mycobacterium tuberculosis, fully inhibited by tyrosine, phenylalanine, and… | x-ray diffraction | A, B | CL, SO4, TRP, MN, PHE, TYR | 12 (best 0.77) |
| 5CKV | Dahp synthase from mycobacterium tuberculosis, fully inhibited by tyrosine, phenylalanine, and… | x-ray diffraction | A, B | — | — |
| 5CKX | Non-covalent complex of DAHP synthase and chorismate mutase from Mycobacterium tuberculosis with… | x-ray diffraction | A, B | MN, CL, SO4, PHE, TYR | 18 (best 0.70) |
| 5CKX | Non-covalent complex of dahp synthase and chorismate mutase from mycobacterium tuberculosis with… | x-ray diffraction | A, B | — | — |
| O53512 | AlphaFold monomer V2.0 prediction for phospho-2-dehydro-3-deoxyheptonate aldolase arog (O53512) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5CKV chain B against the predicted model O53512: TM-score 0.99, RMSD 0.77 Å
- 2W1A chain B against the predicted model O53512: TM-score 0.99, RMSD 0.80 Å
- 2W1A chain B against the predicted model O53512: TM-score 0.99, RMSD 0.80 Å
- 5CKX chain B against the predicted model O53512: TM-score 0.99, RMSD 0.92 Å
- 5CKV chain A against the predicted model O53512: TM-score 0.99, RMSD 0.97 Å
- 5CKV chain B against the predicted model O53512: TM-score 0.99, RMSD 0.77 Å
- 5CKX chain A against the predicted model O53512: TM-score 0.98, RMSD 1.01 Å
- 5CKX chain B against the predicted model O53512: TM-score 0.98, RMSD 0.92 Å
- 2YPQ chain B against the predicted model O53512: TM-score 0.98, RMSD 0.87 Å
- 2YPQ chain B against the predicted model O53512: TM-score 0.98, RMSD 0.87 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.