UniProt O50657
Lysine/ornithine decarboxylase (O50657)
Lysine/ornithine decarboxylase (UniProt O50657), EC 4.1.1.18: 8 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O50657
- Protein
- Lysine/ornithine decarboxylase
- EC
- 4.1.1.18
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 13 · 2 records with a druggable one
Structures
9 records of O50657 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GJM | Crystal structure of Lysine decarboxylase from Selenomonas ruminantium in C2 space group | x-ray diffraction | A, B | — | 10 (best 0.73) |
| 5GJM | Crystal structure of lysine decarboxylase from selenomonas ruminantium in C2 space group | x-ray diffraction | A, B | — | — |
| 5GJN | Crystal structure of Lysine decarboxylase from Selenomonas ruminantium in P43212 space group | x-ray diffraction | A | MG | — |
| 5GJN | Crystal structure of lysine decarboxylase from selenomonas ruminantium in P43212 space group | x-ray diffraction | A | — | — |
| 5GJO | Crystal structure of SrLDC mutant (A225C/T302C) in complex with PLP | x-ray diffraction | A, B | SO4, PLP, NA | — |
| 5GJO | Crystal structure of srldc mutant (A225C/T302C) in complex with plp | x-ray diffraction | A, B | — | — |
| 5GJP | Crystal structure of SrLDC in complex with PLP and Cadaverine | x-ray diffraction | A | N2P, PLP, NA, MG | 3 (best 0.53) |
| 5GJP | Crystal structure of srldc in complex with plp and cadaverine | x-ray diffraction | A | — | — |
| O50657 | AlphaFold monomer V2.0 prediction for LYSINE/ORNITHINE decarboxylase (O50657) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5GJO chain B against the predicted model O50657: TM-score 1.00, RMSD 0.20 Å
- 5GJO chain B against the predicted model O50657: TM-score 1.00, RMSD 0.20 Å
- 5GJO chain A against the predicted model O50657: TM-score 1.00, RMSD 0.19 Å
- 5GJO chain A against the predicted model O50657: TM-score 1.00, RMSD 0.19 Å
- 5GJP chain A against the predicted model O50657: TM-score 0.99, RMSD 0.55 Å
- 5GJP chain A against the predicted model O50657: TM-score 0.99, RMSD 0.55 Å
- 5GJM chain A against the predicted model O50657: TM-score 0.98, RMSD 1.29 Å
- 5GJM chain A against the predicted model O50657: TM-score 0.98, RMSD 1.29 Å
- 5GJN chain A against the predicted model O50657: TM-score 0.98, RMSD 1.40 Å
- 5GJN chain A against the predicted model O50657: TM-score 0.98, RMSD 1.40 Å
Elsewhere
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