UniProt O43920
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (O43920)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (UniProt O43920): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O43920
- Protein
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 4 records with a druggable one
Structures
7 records of O43920 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | h | PLX | 4 (best 0.86) |
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | h | PLX | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | h | PLX | 3 (best 0.86) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | h | PLX | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | h | PLX | 1 (best 0.86) |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | h, Bh | PLX | 2 (best 0.87) |
| O43920 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (O43920) | predicted | A | — | — |
Ligands
- PLX · (9R,11S)-9-({[(1S)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol · in 6 records
Experiment against prediction
- 5XTI chain h against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
- 5XTI chain Bh against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
- 5XTH chain h against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
- 5XTD chain h against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
- 5XTD chain h against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
- 5XTC chain h against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
- 5XTC chain h against the predicted model O43920: TM-score 0.92, RMSD 1.07 Å
Elsewhere
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