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UniProt O43813

Glutathione S-transferase LANCL1 (O43813)

Glutathione S-transferase LANCL1 (UniProt O43813), EC 2.5.1.18: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
O43813
Protein
Glutathione S-transferase LANCL1
EC
2.5.1.18
Experimental structures
8
Predicted models
1
Ligands
3
Pockets
30 · 5 records with a druggable one

Structures

9 records of O43813 in the MolNFT archive: 8 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
3E6UCrystal structure of Human LanCL1x-ray diffractionA, C, B, D——
3E6UCrystal structure of human LANCL1x-ray diffractionA, C, B, D——
3E73Crystal Structure of Human LanCL1 complexed with GSHx-ray diffractionA, B——
3E73Crystal structure of human LANCL1 complexed with gshx-ray diffractionA, B——
8CZKHuman LanCL1 bound to GSH and Dhb-Erk peptidex-ray diffractionA, BZN, GSH8 (best 0.63)
8CZLHuman LanCL1 bound to methyl glutathione (MeGSH)x-ray diffractionA, BZN, GSM4 (best 0.70)
8D0VHuman LanCL1 C264A mutant bound to GSHx-ray diffractionA, BZN, GSH7 (best 0.69)
8D19Human LanCL1 bound to GSHx-ray diffractionA, BZN, GSH8 (best 0.68)
O43813AlphaFold monomer V2.0 prediction for glutathione S-transferase LANCL1 (O43813)predictedA—3 (best 0.58)

Ligands

  • ZN · Zinc ion · in 4 records
  • GSH · Glutathione · in 3 records
  • GSM · L-gamma-glutamyl-S-methylcysteinylglycine · in 1 record

Experiment against prediction

Elsewhere

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