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UniProt O43776

Asparagine--tRNA ligase, cytoplasmic (O43776)

Asparagine--tRNA ligase, cytoplasmic (UniProt O43776), EC 6.1.1.22: 8 experimental structures on GenesisL1, 6 ligands bound, 79 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
O43776
Protein
Asparagine--tRNA ligase, cytoplasmic
EC
6.1.1.22
Experimental structures
8
Predicted models
0
Ligands
6
Pockets
79 · 4 records with a druggable one

Structures

8 records of O43776 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4ZYAThe N-terminal extension domain of human asparaginyl-tRNA synthetasex-ray diffractionA, B——
4ZYAThe N-terminal extension domain of human asparaginyl-tRNA synthetasex-ray diffractionA, B——
5XIXThe canonical domain of human asparaginyl-tRNA synthetasex-ray diffractionA, B, C, D—20 (best 0.79)
5XIXThe canonical domain of human asparaginyl-tRNA synthetasex-ray diffractionA, B, C, D——
8H53Human asparaginyl-tRNA synthetase in complex with asparagine-AMPx-ray diffractionA, B, C, D4AD, 2PN, MG19 (best 0.79)
8TC7Human asparaginyl-tRNA synthetase, apo formx-ray diffractionA, B, C, DCL20 (best 0.80)
8TC8Human asparaginyl-tRNA synthetase bound to adenosine 5'-sulfamatex-ray diffractionA, B, C, DNSS, NA20 (best 0.79)
O43776AlphaFold monomer V2.0 prediction for asparagine--tRNA ligase, cytoplasmic (O43776)———

Ligands

  • 2PN · Imidodiphosphoric acid · in 1 record
  • 4AD · 4-amino-1,4-dioxobutan-2-aminium adenosine-5'-monophosphate · in 1 record
  • CL · Chloride ion · in 1 record
  • MG · Magnesium ion · in 1 record
  • NA · Sodium ion · in 1 record
  • NSS · 5'-O-[N-(L-asparaginyl)sulfamoyl]adenosine · in 1 record

Elsewhere

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