UniProt O43719
HIV Tat-specific factor 1 (O43719)
HIV Tat-specific factor 1 (UniProt O43719): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43719
- Protein
- HIV Tat-specific factor 1
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 4 records with a druggable one
Structures
19 records of O43719 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6N3D | Structure of HIV Tat-specific factor 1 U2AF Homology Motif (APO-State) | x-ray diffraction | A | CL, MG | — |
| 6N3D | Structure of HIV tat-specific factor 1 U2AF homology motif (apo-state) | x-ray diffraction | A | CL, MG | — |
| 6N3E | Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4 | x-ray diffraction | A | — | — |
| 6N3E | Structure of HIV tat-specific factor 1 U2AF homology motif bound to U2AF ligand motif 4 | x-ray diffraction | A | — | — |
| 6N3F | Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to SF3b1 ULM5 | x-ray diffraction | A, C | — | 2 (best 0.49) |
| 6N3F | Structure of HIV tat-specific factor 1 U2AF homology motif bound to SF3B1 ULM5 | x-ray diffraction | A, C | — | — |
| 6NSX | Yeast HSH155 ligand bound to human tat-SF1 motif | x-ray diffraction | A | CL | — |
| 6Y50 | 5'domain of human 17S U2 snRNP | electron microscopy | q | — | 1 (best 0.83) |
| 6Y50 | 5'DOMAIN of human 17S U2 snrnp | electron microscopy | q | — | — |
| 6Y53 | human 17S U2 snRNP low resolution part | electron microscopy | q | — | 1 (best 0.55) |
| 6Y53 | Human 17S U2 snrnp low resolution part | electron microscopy | q | — | — |
| 6Y5Q | human 17S U2 snRNP | electron microscopy | q | — | — |
| 6Y5Q | Human 17S U2 snrnp | electron microscopy | q | — | — |
| 7EVO | The cryo-EM structure of the human 17S U2 snRNP | electron microscopy | D | — | — |
| 7EVO | The cryo-EM structure of the human 17S U2 snrnp | electron microscopy | D | — | — |
| 7Q3L | Human 17S U2 snRNP 5' domain | electron microscopy | q | — | 3 (best 0.79) |
| 7Q3L | Human 17S U2 snrnp 5' domain | electron microscopy | q | — | — |
| 8HK1 | The cryo-EM structure of human pre-17S U2 snRNP | electron microscopy | D | — | 1 (best 0.71) |
| O43719 | AlphaFold monomer V2.0 prediction for HIV tat-specific factor 1 (O43719) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6Y53 chain q against the predicted model O43719: TM-score 0.97, RMSD 0.59 Å
- 6Y53 chain q against the predicted model O43719: TM-score 0.97, RMSD 0.59 Å
- 6NSX chain A against the predicted model O43719: TM-score 0.96, RMSD 0.98 Å
- 6N3E chain A against the predicted model O43719: TM-score 0.96, RMSD 1.00 Å
- 6N3E chain A against the predicted model O43719: TM-score 0.96, RMSD 1.00 Å
- 6N3D chain A against the predicted model O43719: TM-score 0.96, RMSD 0.78 Å
- 6N3D chain A against the predicted model O43719: TM-score 0.96, RMSD 0.78 Å
- 6N3F chain C against the predicted model O43719: TM-score 0.96, RMSD 0.92 Å
- 6N3F chain C against the predicted model O43719: TM-score 0.96, RMSD 0.92 Å
- 7Q3L chain q against the predicted model O43719: TM-score 0.94, RMSD 0.74 Å
Elsewhere
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