UniProt O43678
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (O43678)
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (UniProt O43678): 7 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O43678
- Protein
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
8 records of O43678 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1S3A | NMR Solution Structure of Subunit B8 from Human NADH-Ubiqui Oxidoreductase Complex I (CI-B8) | solution nmr | A | — | — |
| 1S3A | NMR solution structure of subunit B8 from human NADH-ubiquinone oxidoreductase complex I (ci-B8) | solution nmr | A | — | — |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | F | — | — |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | F | — | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | F | — | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | F | — | — |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | F, BF | — | — |
| O43678 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2… | predicted | A | — | 1 (best 0.31) |
Experiment against prediction
- 5XTI chain F against the predicted model O43678: TM-score 0.92, RMSD 1.15 Å
- 5XTH chain F against the predicted model O43678: TM-score 0.92, RMSD 1.15 Å
- 5XTD chain F against the predicted model O43678: TM-score 0.92, RMSD 1.15 Å
- 5XTI chain BF against the predicted model O43678: TM-score 0.92, RMSD 1.15 Å
- 5XTB chain F against the predicted model O43678: TM-score 0.92, RMSD 1.15 Å
- 5XTB chain F against the predicted model O43678: TM-score 0.92, RMSD 1.15 Å
- 1S3A chain A against the predicted model O43678: TM-score 0.69, RMSD 2.65 Å
- 1S3A chain A against the predicted model O43678: TM-score 0.69, RMSD 2.65 Å
Elsewhere
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