UniProt O43674
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (O43674)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (UniProt O43674): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment…
- UniProt
- O43674
- Protein
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 4 records with a druggable one
Structures
7 records of O43674 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | a | PLX, CDL | 6 (best 0.86) |
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | a | PLX, CDL | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | a | PLX, CDL | 4 (best 0.89) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | a | PLX, CDL | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | a | PLX, CDL | 3 (best 0.87) |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | a, Ba | PLX, CDL | 3 (best 0.89) |
| O43674 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5XTD chain a against the predicted model O43674: TM-score 0.94, RMSD 1.13 Å
- 5XTD chain a against the predicted model O43674: TM-score 0.94, RMSD 1.13 Å
- 5XTH chain a against the predicted model O43674: TM-score 0.94, RMSD 1.13 Å
- 5XTI chain Ba against the predicted model O43674: TM-score 0.94, RMSD 1.13 Å
- 5XTI chain a against the predicted model O43674: TM-score 0.94, RMSD 1.14 Å
- 5XTC chain a against the predicted model O43674: TM-score 0.94, RMSD 1.14 Å
- 5XTC chain a against the predicted model O43674: TM-score 0.94, RMSD 1.14 Å
Elsewhere
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