UniProt O43602
Neuronal migration protein doublecortin (O43602)
Neuronal migration protein doublecortin (UniProt O43602): 28 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43602
- Protein
- Neuronal migration protein doublecortin
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 26 · 6 records with a druggable one
Structures
29 records of O43602 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MJD | Structure of N-terminal domain of human doublecortin | solution nmr | A | — | — |
| 1MJD | Structure of N-terminal domain of human doublecortin | solution nmr | A | — | — |
| 2BQQ | X-ray Structure of the N-terminal Domain of Human Doublecortin | x-ray diffraction | A | — | — |
| 2BQQ | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A | — | — |
| 2XRP | Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the… | electron microscopy | I | — | — |
| 2XRP | Human doublecortin N-dc repeat (1MJD) and mammalian tubulin (1JFF and 3HKE) docked into the… | electron microscopy | I | — | — |
| 4ATU | Human doublecortin N-DC repeat plus linker, and tubulin (2XRP) docked into an 8A cryo-EM map of… | electron microscopy | I | — | — |
| 4ATU | Human doublecortin N-dc repeat plus linker, and tubulin (2XRP) docked into an 8A cryo-EM MAP of… | electron microscopy | I | — | — |
| 5IKC | X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB | x-ray diffraction | M, N | CL | 6 (best 0.51) |
| 5IKC | X-ray structure of the N-terminal domain of human doublecortin in complex with Fab | x-ray diffraction | M, N | — | — |
| 5IN7 | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A, B | — | — |
| 5IN7 | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A, B | — | — |
| 5IO9 | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A, B | — | — |
| 5IO9 | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A, B | — | — |
| 5IOI | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5IOI | X-ray structure of the N-terminal domain of human doublecortin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5IP4 | X-ray structure of the C-terminal domain of human doublecortin | x-ray diffraction | D, E | — | — |
| 5IP4 | X-ray structure of the C-terminal domain of human doublecortin | x-ray diffraction | D, E | — | — |
| 6FNZ | Crystal Structure of domain-swapped C-terminal domain of human doublecortin | x-ray diffraction | A, B, C, D | — | 4 (best 0.68) |
| 6FNZ | Crystal structure of domain-swapped C-terminal domain of human doublecortin | x-ray diffraction | A, B, C, D | — | — |
| 6REV | Cryo-EM structure of the N-terminal DC repeat (NDC) of human doublecortin (DCX) bound to… | electron microscopy | N | — | 5 (best 0.80) |
| 6REV | Cryo-EM structure of the N-terminal dc repeat (ndc) of human doublecortin (dcx) bound to… | electron microscopy | N | — | — |
| 6RF2 | Cryo-EM structure of the C-terminal DC repeat (CDC) of human doublecortin (DCX) bound to… | electron microscopy | C | — | 2 (best 0.80) |
| 6RF2 | Cryo-EM structure of the C-terminal dc repeat (cdc) of human doublecortin (dcx) bound to… | electron microscopy | C | — | — |
| 6RF8 | Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to… | electron microscopy | N | — | 5 (best 0.82) |
| 6RF8 | Cryo-EM structure of the N-terminal dc repeat (ndc) of ndc-ndc chimera (human sequence) bound to… | electron microscopy | N | — | — |
| 6RFD | Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to… | electron microscopy | N | — | 4 (best 0.80) |
| 6RFD | Cryo-EM structure of the N-terminal dc repeat (ndc) of ndc-ndc chimera (human sequence) bound to… | electron microscopy | N | — | — |
| O43602 | AlphaFold monomer V2.0 prediction for neuronal migration protein doublecortin (O43602) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 1 record
Experiment against prediction
- 5IOI chain C against the predicted model O43602: TM-score 0.98, RMSD 0.54 Å
- 5IOI chain C against the predicted model O43602: TM-score 0.98, RMSD 0.54 Å
- 5IKC chain M against the predicted model O43602: TM-score 0.98, RMSD 0.55 Å
- 5IKC chain M against the predicted model O43602: TM-score 0.98, RMSD 0.55 Å
- 5IKC chain N against the predicted model O43602: TM-score 0.97, RMSD 0.59 Å
- 5IKC chain N against the predicted model O43602: TM-score 0.97, RMSD 0.59 Å
- 5IOI chain F against the predicted model O43602: TM-score 0.97, RMSD 0.60 Å
- 5IOI chain F against the predicted model O43602: TM-score 0.97, RMSD 0.60 Å
- 5IO9 chain A against the predicted model O43602: TM-score 0.97, RMSD 0.71 Å
- 5IO9 chain A against the predicted model O43602: TM-score 0.97, RMSD 0.71 Å
Elsewhere
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