UniProt O43543
DNA repair protein XRCC2 (O43543)
DNA repair protein XRCC2 (UniProt O43543): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43543
- Protein
- DNA repair protein XRCC2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 22 · 4 records with a druggable one
Structures
5 records of O43543 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FAZ | Cryo-EM structure of the human BCDX2 complex | electron microscopy | X | ANP, MG | 5 (best 0.77) |
| 8GBJ | Cryo-EM structure of a human BCDX2/ssDNA complex | electron microscopy | X | ANP | 5 (best 0.76) |
| 8OUY | Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution | electron microscopy | D | MG, ATP | 5 (best 0.78) |
| 8OUZ | Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 2.2 A resolution | electron microscopy | D | ATP, MG | 5 (best 0.76) |
| O43543 | AlphaFold monomer V2.0 prediction for DNA repair protein XRCC2 (O43543) | predicted | A | — | 2 (best 0.38) |
Ligands
Experiment against prediction
- 8GBJ chain X against the predicted model O43543: TM-score 0.98, RMSD 0.84 Å
- 8FAZ chain X against the predicted model O43543: TM-score 0.98, RMSD 0.95 Å
- 8OUZ chain D against the predicted model O43543: TM-score 0.97, RMSD 1.25 Å
- 8OUY chain D against the predicted model O43543: TM-score 0.96, RMSD 1.38 Å
Elsewhere
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