UniProt O43402
ER membrane protein complex subunit 8 (O43402)
ER membrane protein complex subunit 8 (UniProt O43402): 11 experimental structures and 1 predicted model on GenesisL1, 41 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43402
- Protein
- ER membrane protein complex subunit 8
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 41 · 8 records with a druggable one
Structures
12 records of O43402 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WW7 | Structure of the human ER membrane protein complex in a lipid nanodisc | electron microscopy | H | — | 5 (best 0.75) |
| 6WW7 | Structure of the human er membrane protein complex in a lipid nanodisc | electron microscopy | H | — | — |
| 7ADO | Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs | electron microscopy | H | — | 7 (best 0.77) |
| 7ADO | Cryo-EM structure of human er membrane protein complex in lipid nanodiscs | electron microscopy | H | — | — |
| 7ADP | Cryo-EM structure of human ER membrane protein complex in GDN detergent | electron microscopy | H | — | 8 (best 0.75) |
| 7ADP | Cryo-EM structure of human er membrane protein complex in gdn detergent | electron microscopy | H | — | — |
| 8EOI | Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | electron microscopy | H | — | 4 (best 0.78) |
| 8J0N | cryo-EM structure of human EMC | electron microscopy | H | — | 5 (best 0.80) |
| 8J0O | cryo-EM structure of human EMC and VDAC | electron microscopy | H | — | 4 (best 0.79) |
| 8S9S | Structure of the human ER membrane protein complex (EMC) in GDN | electron microscopy | 8 | — | 3 (best 0.74) |
| 9C7V | Structure of the human BOS:human EMC complex in GDN | electron microscopy | 8 | — | 5 (best 0.73) |
| O43402 | AlphaFold monomer V2.0 prediction for er membrane protein complex subunit 8 (O43402) | predicted | A | — | — |
Experiment against prediction
- 9C7V chain 8 against the predicted model O43402: TM-score 0.97, RMSD 0.86 Å
- 8S9S chain 8 against the predicted model O43402: TM-score 0.97, RMSD 0.89 Å
- 8EOI chain H against the predicted model O43402: TM-score 0.97, RMSD 0.97 Å
- 6WW7 chain H against the predicted model O43402: TM-score 0.96, RMSD 1.11 Å
- 6WW7 chain H against the predicted model O43402: TM-score 0.96, RMSD 1.11 Å
- 7ADO chain H against the predicted model O43402: TM-score 0.96, RMSD 1.07 Å
- 7ADO chain H against the predicted model O43402: TM-score 0.96, RMSD 1.07 Å
- 7ADP chain H against the predicted model O43402: TM-score 0.94, RMSD 1.22 Å
- 7ADP chain H against the predicted model O43402: TM-score 0.94, RMSD 1.22 Å
- 8J0O chain H against the predicted model O43402: TM-score 0.94, RMSD 1.47 Å
Elsewhere
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