UniProt O43396
Thioredoxin-like protein 1 (O43396)
Thioredoxin-like protein 1 (UniProt O43396): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43396
- Protein
- Thioredoxin-like protein 1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 8 records with a druggable one
Structures
13 records of O43396 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GH2 | Crystal structure of the catalytic domain of a new human thioredoxin-like protein | x-ray diffraction | A | — | — |
| 1GH2 | Crystal structure of the catalytic domain of a new human thioredoxin-like protein | x-ray diffraction | A | — | — |
| 1WWY | Solution structure of the DUF1000 domain of a thioredoxin-like protein 1 | solution nmr | A | — | — |
| 1WWY | Solution structure of the DUF1000 domain of a thioredoxin-like protein 1 | solution nmr | A | — | — |
| 9E8G | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt5 at top of spiral staircase | electron microscopy | u | ZN | 1 (best 0.79) |
| 9E8H | Human proteasome in resting state conformation bound to TXNL1 in backward conformation | electron microscopy | u | — | 1 (best 0.77) |
| 9E8I | Human proteasome in resting state conformation bound to TXNL1 in Forward conformation | electron microscopy | u | — | 1 (best 0.80) |
| 9E8J | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt1 at top of spiral staircase | electron microscopy | u | ZN | 3 (best 0.77) |
| 9E8K | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt6 at top of spiral staircase | electron microscopy | u | — | 2 (best 0.84) |
| 9E8L | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase | electron microscopy | u | ZN | 2 (best 0.84) |
| 9E8N | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt3 at top of spiral staircase | electron microscopy | u | ZN | 2 (best 0.80) |
| 9E8O | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt2 at top of spiral staircase and… | electron microscopy | u | — | 1 (best 0.77) |
| O43396 | AlphaFold monomer V2.0 prediction for thioredoxin-like protein 1 (O43396) | predicted | A | — | 1 (best 0.27) |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 1GH2 chain A against the predicted model O43396: TM-score 0.99, RMSD 0.48 Å
- 1GH2 chain A against the predicted model O43396: TM-score 0.99, RMSD 0.48 Å
- 9E8O chain u against the predicted model O43396: TM-score 0.98, RMSD 0.75 Å
- 9E8I chain u against the predicted model O43396: TM-score 0.97, RMSD 0.81 Å
- 9E8H chain u against the predicted model O43396: TM-score 0.97, RMSD 0.90 Å
- 9E8L chain u against the predicted model O43396: TM-score 0.88, RMSD 1.12 Å
- 9E8G chain u against the predicted model O43396: TM-score 0.88, RMSD 1.11 Å
- 9E8J chain u against the predicted model O43396: TM-score 0.88, RMSD 1.13 Å
- 9E8N chain u against the predicted model O43396: TM-score 0.86, RMSD 1.41 Å
- 9E8K chain u against the predicted model O43396: TM-score 0.86, RMSD 1.43 Å
Elsewhere
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