UniProt O43043
Sterol regulatory element-binding protein cleavage-activating protein (O43043)
Sterol regulatory element-binding protein cleavage-activating protein (UniProt O43043): 4 experimental structures and 1 predicted model on GenesisL1, 33 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O43043
- Protein
- Sterol regulatory element-binding protein cleavage-activating protein
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 33 · 2 records with a druggable one
Structures
5 records of O43043 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4YHC | Crystal structure of the WD40 domain of SCAP from fission yeast | x-ray diffraction | A, B | — | — |
| 4YHC | Crystal structure of the WD40 domain of scap from fission yeast | x-ray diffraction | A, B | — | — |
| 5GRS | Complex structure of the fission yeast SREBP-SCAP binding domains | electron microscopy | A, I, B, J, C, K, D, L | — | 19 (best 0.83) |
| 5GRS | Complex structure of the fission yeast srebp-scap binding domains | electron microscopy | A, I, B, J, C, K, D, L | — | — |
| O43043 | AlphaFold monomer V2.0 prediction for sterol regulatory element- binding protein… | predicted | A | — | 14 (best 0.76) |
Experiment against prediction
- 4YHC chain A against the predicted model O43043: TM-score 0.99, RMSD 1.07 Å
- 4YHC chain A against the predicted model O43043: TM-score 0.99, RMSD 1.07 Å
- 4YHC chain B against the predicted model O43043: TM-score 0.97, RMSD 1.12 Å
- 4YHC chain B against the predicted model O43043: TM-score 0.97, RMSD 1.12 Å
- 5GRS chain B against the predicted model O43043: TM-score 0.95, RMSD 1.60 Å
- 5GRS chain A against the predicted model O43043: TM-score 0.95, RMSD 1.60 Å
- 5GRS chain A against the predicted model O43043: TM-score 0.95, RMSD 1.60 Å
- 5GRS chain D against the predicted model O43043: TM-score 0.95, RMSD 1.60 Å
- 5GRS chain C against the predicted model O43043: TM-score 0.95, RMSD 1.60 Å
- 5GRS chain L against the predicted model O43043: TM-score 0.89, RMSD 0.98 Å
Elsewhere
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