UniProt O42861
ATP-dependent helicase fft3 (O42861)
ATP-dependent helicase fft3 (UniProt O42861), EC 3.6.4.12: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O42861
- Protein
- ATP-dependent helicase fft3
- EC
- 3.6.4.12
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
4 records of O42861 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XWY | Crystal structure of spFft3 N-terminal truncation | x-ray diffraction | A | SO4 | 1 (best 0.47) |
| 7XXE | Crystal structure of spFft3 C-terminal truncation | x-ray diffraction | B, A | — | 9 (best 0.72) |
| 7XYG | Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome | electron microscopy | K | — | 2 (best 0.72) |
| O42861 | AlphaFold monomer V2.0 prediction for ATP-dependent helicase FFT3 (O42861) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 7XXE chain B against the predicted model O42861: TM-score 0.88, RMSD 2.63 Å
- 7XXE chain A against the predicted model O42861: TM-score 0.87, RMSD 2.72 Å
- 7XWY chain A against the predicted model O42861: TM-score 0.87, RMSD 3.01 Å
- 7XYG chain K against the predicted model O42861: TM-score 0.75, RMSD 5.30 Å
Elsewhere
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