UniProt O39929
Non-structural protein 4A,Serine protease NS3 (O39929)
Non-structural protein 4A,Serine protease NS3 (UniProt O39929), EC 3.4.21.98, 3.6.1.15: 4 experimental structures on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O39929
- Protein
- Non-structural protein 4A,Serine protease NS3
- EC
- 3.4.21.98, 3.6.1.15, 3.6.4.13
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 3 · 0 records with a druggable one
Structures
4 records of O39929 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6P6T | HCV NS3/4A protease domain of genotype 4a in complex with glecaprevir | x-ray diffraction | A | ZN, O31 | 2 (best 0.31) |
| 6P6T | HCV NS3/4A protease domain of genotype 4A in complex with glecaprevir | x-ray diffraction | A | ZN, O31 | — |
| 6P6Z | HCV NS3/4A protease domain of genotype 4a with an extended linker in complex with glecaprevir | x-ray diffraction | A | ZN, O31 | 1 (best 0.31) |
| 6P6Z | HCV NS3/4A protease domain of genotype 4A with an extended linker in complex with glecaprevir | x-ray diffraction | A | ZN, O31 | — |
Ligands
- O31 · (3ar,7s,10s,12r,21e,24ar)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl) sulfonyl]carbamoyl}cyclopropyl]-20,20-difluoro-5,8-dioxo-2,3,3A,5,6,7,8,11,12,20,23,24A-dodecahydro-1H, 10H-9,12-methanocyclopenta[18,19][1,10,17,3, 6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide · in 4 records
- ZN · Zinc ion · in 4 records
Elsewhere
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