UniProt O35405
5'-3' exonuclease PLD3 (O35405)
5'-3' exonuclease PLD3 (UniProt O35405), EC 3.-.-.-: 3 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O35405
- Protein
- 5'-3' exonuclease PLD3
- EC
- 3.-.-.-
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 28 · 3 records with a druggable one
Structures
4 records of O35405 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8V05 | Crystal structure of mouse PLD3 | x-ray diffraction | A | NAG, BMA, MAN, CYS | 2 (best 0.55) |
| 8V06 | Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days | x-ray diffraction | A, B, C, D | NAG, BMA, MAN, PO4 | 11 (best 0.53) |
| 8V07 | Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 30 days | x-ray diffraction | B, A, C, D | NAG, BMA, MAN, ACE, PO4 | 12 (best 0.50) |
| O35405 | AlphaFold monomer V2.0 prediction for 5'-3' exonuclease PLD3 (O35405) | predicted | A | — | 3 (best 0.56) |
Ligands
Experiment against prediction
- 8V06 chain A against the predicted model O35405: TM-score 0.99, RMSD 0.79 Å
- 8V07 chain A against the predicted model O35405: TM-score 0.99, RMSD 0.79 Å
- 8V07 chain B against the predicted model O35405: TM-score 0.99, RMSD 0.80 Å
- 8V06 chain C against the predicted model O35405: TM-score 0.99, RMSD 0.81 Å
- 8V07 chain D against the predicted model O35405: TM-score 0.99, RMSD 0.80 Å
- 8V07 chain C against the predicted model O35405: TM-score 0.99, RMSD 0.82 Å
- 8V06 chain B against the predicted model O35405: TM-score 0.99, RMSD 0.85 Å
- 8V06 chain D against the predicted model O35405: TM-score 0.99, RMSD 0.86 Å
- 8V05 chain A against the predicted model O35405: TM-score 0.97, RMSD 1.07 Å
Elsewhere
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