UniProt O31677
7-carboxy-7-deazaguanine synthase (O31677)
7-carboxy-7-deazaguanine synthase (UniProt O31677), EC 4.3.99.3: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O31677
- Protein
- 7-carboxy-7-deazaguanine synthase
- EC
- 4.3.99.3
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 14 · 3 records with a druggable one
Structures
5 records of O31677 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TGS | Crystal Structure of QueE from Bacillus subtilis with methionine bound | x-ray diffraction | A, B | SF4, MET | 4 (best 0.79) |
| 5TGS | Crystal structure of quee from bacillus subtilis with methionine bound | x-ray diffraction | A, B | SF4 | — |
| 5TH5 | Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound | x-ray diffraction | A, B, C, D | SF4, 7C5, MET | 9 (best 0.84) |
| 5TH5 | Crystal structure of quee from bacillus subtilis with 6-carboxypterin- 5'-deoxyadenosyl ester bound | x-ray diffraction | A, B, C, D | SF4, 7C5 | — |
| O31677 | AlphaFold monomer V2.0 prediction for 7-carboxy-7-deazaguanine synthase (O31677) | predicted | A | — | 1 (best 0.82) |
Ligands
Experiment against prediction
- 5TH5 chain A against the predicted model O31677: TM-score 0.99, RMSD 0.45 Å
- 5TGS chain B against the predicted model O31677: TM-score 0.99, RMSD 0.52 Å
- 5TGS chain B against the predicted model O31677: TM-score 0.99, RMSD 0.52 Å
- 5TH5 chain A against the predicted model O31677: TM-score 0.99, RMSD 0.45 Å
- 5TGS chain A against the predicted model O31677: TM-score 0.98, RMSD 0.90 Å
- 5TGS chain A against the predicted model O31677: TM-score 0.98, RMSD 0.90 Å
Elsewhere
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