UniProt O26347
Phosphoribosyl-AMP cyclohydrolase (O26347)
Phosphoribosyl-AMP cyclohydrolase (UniProt O26347), EC 3.5.4.19: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O26347
- Protein
- Phosphoribosyl-AMP cyclohydrolase
- EC
- 3.5.4.19
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
3 records of O26347 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZPS | Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI | x-ray diffraction | A, B | CD | 2 (best 0.60) |
| 1ZPS | Crystal structure of methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase hisi | x-ray diffraction | A, B | — | — |
| O26347 | AlphaFold monomer V2.0 prediction for phosphoribosyl-AMP cyclohydrolase (O26347) | predicted | A | — | — |
Ligands
- CD · Cadmium ion · in 1 record
Experiment against prediction
- 1ZPS chain A against the predicted model O26347: TM-score 0.99, RMSD 0.43 Å
- 1ZPS chain A against the predicted model O26347: TM-score 0.99, RMSD 0.43 Å
- 1ZPS chain B against the predicted model O26347: TM-score 0.97, RMSD 1.13 Å
- 1ZPS chain B against the predicted model O26347: TM-score 0.97, RMSD 1.13 Å
Elsewhere
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