UniProt O25294
Cytosol aminopeptidase (O25294)
Cytosol aminopeptidase (UniProt O25294), EC 3.4.11.1, 3.4.11.10: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O25294
- Protein
- Cytosol aminopeptidase
- EC
- 3.4.11.1, 3.4.11.10
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of O25294 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ZI6 | Crystal structure of leucine aminopeptidase from Helicobacter pylori | x-ray diffraction | A, B, C, D, E, F | ZN, BCT, NA | 20 (best 0.73) |
| 4ZI6 | Crystal structure of leucine aminopeptidase from helicobacter pylori | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4ZLA | Bestatin complex structure of leucine aminopeptidase from Helicobacter pylori | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4ZLA | Bestatin complex structure of leucine aminopeptidase from helicobacter pylori | x-ray diffraction | A, B, C, D, E, F | — | — |
| O25294 | AlphaFold monomer V2.0 prediction for cytosol aminopeptidase (O25294) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4ZI6 chain D against the predicted model O25294: TM-score 0.99, RMSD 0.60 Å
- 4ZI6 chain D against the predicted model O25294: TM-score 0.99, RMSD 0.60 Å
- 4ZI6 chain F against the predicted model O25294: TM-score 0.99, RMSD 0.61 Å
- 4ZI6 chain F against the predicted model O25294: TM-score 0.99, RMSD 0.61 Å
- 4ZLA chain D against the predicted model O25294: TM-score 0.99, RMSD 0.62 Å
- 4ZLA chain D against the predicted model O25294: TM-score 0.99, RMSD 0.62 Å
- 4ZLA chain F against the predicted model O25294: TM-score 0.99, RMSD 0.62 Å
- 4ZLA chain F against the predicted model O25294: TM-score 0.99, RMSD 0.62 Å
- 4ZLA chain B against the predicted model O25294: TM-score 0.99, RMSD 0.63 Å
- 4ZLA chain B against the predicted model O25294: TM-score 0.99, RMSD 0.63 Å
Elsewhere
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