UniProt O18423
Lysenin (O18423)
Lysenin (UniProt O18423): 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O18423
- Protein
- Lysenin
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 21 · 1 record with a druggable one
Structures
10 records of O18423 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZX7 | Complex of lysenin with phosphocholine | x-ray diffraction | A | — | — |
| 3ZX7 | Complex of lysenin with phosphocholine | x-ray diffraction | A | — | — |
| 3ZXD | wild-type lysenin | x-ray diffraction | A, B, C, D | — | — |
| 3ZXD | Wild-type lysenin | x-ray diffraction | A, B, C, D | — | — |
| 3ZXG | lysenin sphingomyelin complex | x-ray diffraction | A, B | — | — |
| 3ZXG | Lysenin sphingomyelin complex | x-ray diffraction | A, B | — | — |
| 5EC5 | Crystal structure of lysenin pore | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, R, S | MBO, HG | 20 (best 0.81) |
| 5EC5 | Crystal structure of lysenin pore | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, R, S | — | — |
| 5GAQ | Cryo-EM structure of the lysenin pore | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| O18423 | AlphaFold monomer V2.0 prediction for lysenin (O18423) | predicted | A | — | 1 (best 0.36) |
Ligands
Experiment against prediction
- 5EC5 chain E against the predicted model O18423: TM-score 0.98, RMSD 0.82 Å
- 5EC5 chain E against the predicted model O18423: TM-score 0.98, RMSD 0.82 Å
- 5EC5 chain I against the predicted model O18423: TM-score 0.98, RMSD 0.85 Å
- 5EC5 chain I against the predicted model O18423: TM-score 0.98, RMSD 0.85 Å
- 5GAQ chain A against the predicted model O18423: TM-score 0.98, RMSD 0.95 Å
- 5EC5 chain D against the predicted model O18423: TM-score 0.98, RMSD 0.93 Å
- 5EC5 chain D against the predicted model O18423: TM-score 0.98, RMSD 0.93 Å
- 5EC5 chain B against the predicted model O18423: TM-score 0.98, RMSD 0.92 Å
- 5EC5 chain B against the predicted model O18423: TM-score 0.98, RMSD 0.92 Å
- 5EC5 chain F against the predicted model O18423: TM-score 0.98, RMSD 0.93 Å
Elsewhere
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