UniProt O15438
ATP-binding cassette sub-family C member 3 (O15438)
ATP-binding cassette sub-family C member 3 (UniProt O15438), EC 7.6.2.-, 7.6.2.2: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 56 pockets. Binding sites, druggability and experiment against…
- UniProt
- O15438
- Protein
- ATP-binding cassette sub-family C member 3
- EC
- 7.6.2.-, 7.6.2.2, 7.6.2.3
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 56 · 3 records with a druggable one
Structures
3 records of O15438 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8HVH | Cryo-EM structure of ABC transporter ABCC3 | electron microscopy | A | — | 16 (best 0.83) |
| 8HW2 | Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in… | electron microscopy | A | U38 | 20 (best 0.81) |
| O15438 | AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 3 (O15438) | predicted | A | — | 20 (best 0.86) |
Ligands
- U38 · Estradiol-17beta-glucuronide · in 1 record
Experiment against prediction
- 8HW2 chain A against the predicted model O15438: TM-score 0.85, RMSD 3.76 Å
- 8HVH chain A against the predicted model O15438: TM-score 0.79, RMSD 5.26 Å
Elsewhere
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