UniProt O15372
Eukaryotic translation initiation factor 3 subunit H (O15372)
Eukaryotic translation initiation factor 3 subunit H (UniProt O15372): 5 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15372
- Protein
- Eukaryotic translation initiation factor 3 subunit H
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 3 · 3 records with a druggable one
Structures
6 records of O15372 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6YBD | Structure of a human 48S translational initiation complex - EIF3 | electron microscopy | 8 | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | H | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | 8 | — | 1 (best 0.86) |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | 8 | — | 1 (best 0.84) |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | I8 | — | 1 (best 0.86) |
| O15372 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit H (O15372) | predicted | A | — | — |
Experiment against prediction
- 7A09 chain H against the predicted model O15372: TM-score 0.96, RMSD 1.40 Å
- 8PPL chain I8 against the predicted model O15372: TM-score 0.94, RMSD 2.09 Å
- 6YBD chain 8 against the predicted model O15372: TM-score 0.83, RMSD 2.84 Å
- 7QP6 chain 8 against the predicted model O15372: TM-score 0.82, RMSD 2.92 Å
- 7QP7 chain 8 against the predicted model O15372: TM-score 0.81, RMSD 3.01 Å
Elsewhere
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