UniProt O15318
DNA-directed RNA polymerase III subunit RPC7 (O15318)
DNA-directed RNA polymerase III subunit RPC7 (UniProt O15318): 23 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O15318
- Protein
- DNA-directed RNA polymerase III subunit RPC7
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 34 · 13 records with a druggable one
Structures
24 records of O15318 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7A6H | Cryo-EM structure of human apo RNA Polymerase III | electron microscopy | Q | SF4 | 5 (best 0.82) |
| 7A6H | Cryo-EM structure of human apo RNA polymerase III | electron microscopy | Q | — | — |
| 7AE1 | Cryo-EM structure of human RNA Polymerase III elongation complex 1 | electron microscopy | Q | SF4 | 2 (best 0.82) |
| 7AE1 | Cryo-EM structure of human RNA polymerase III elongation complex 1 | electron microscopy | Q | — | — |
| 7AE3 | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | electron microscopy | Q | — | 2 (best 0.85) |
| 7AE3 | Cryo-EM structure of human RNA polymerase III elongation complex 3 | electron microscopy | Q | — | — |
| 7AEA | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | electron microscopy | Q | — | 3 (best 0.83) |
| 7AEA | Cryo-EM structure of human RNA polymerase III elongation complex 2 | electron microscopy | Q | — | — |
| 7D58 | cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | Q | SF4 | 2 (best 0.81) |
| 7D58 | Cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | Q | — | — |
| 7D59 | cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | Q | — | 4 (best 0.86) |
| 7D59 | Cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | Q | — | — |
| 7DN3 | Structure of Human RNA Polymerase III elongation complex | electron microscopy | Q | — | 2 (best 0.81) |
| 7DN3 | Structure of human RNA polymerase III elongation complex | electron microscopy | Q | — | — |
| 7DU2 | RNA polymerase III EC complex in post-translocation state | electron microscopy | Q | — | 3 (best 0.83) |
| 7DU2 | RNA polymerase III ec complex in post-translocation state | electron microscopy | Q | — | — |
| 7FJI | human Pol III elongation complex | electron microscopy | Q | — | 3 (best 0.80) |
| 7FJI | Human pol III elongation complex | electron microscopy | Q | — | — |
| 7FJJ | human Pol III pre-termination complex | electron microscopy | Q | — | 2 (best 0.82) |
| 7FJJ | Human pol III pre-termination complex | electron microscopy | Q | — | — |
| 8ITY | human RNA polymerase III pre-initiation complex closed DNA 1 | electron microscopy | Q | — | 2 (best 0.86) |
| 8IUE | RNA polymerase III pre-initiation complex melting complex 1 | electron microscopy | Q | SF4 | 2 (best 0.81) |
| 8IUH | RNA polymerase III pre-initiation complex open complex 1 | electron microscopy | Q | SF4 | 2 (best 0.82) |
| O15318 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC7 (O15318) | predicted | A | — | — |
Ligands
- SF4 · Iron/sulfur cluster · in 5 records
Experiment against prediction
- 8ITY chain Q against the predicted model O15318: TM-score 0.46, RMSD 3.62 Å
- 8IUH chain Q against the predicted model O15318: TM-score 0.45, RMSD 3.22 Å
- 7D58 chain Q against the predicted model O15318: TM-score 0.44, RMSD 3.59 Å
- 7D58 chain Q against the predicted model O15318: TM-score 0.44, RMSD 3.59 Å
- 8IUE chain Q against the predicted model O15318: TM-score 0.44, RMSD 3.41 Å
- 7A6H chain Q against the predicted model O15318: TM-score 0.41, RMSD 4.03 Å
- 7A6H chain Q against the predicted model O15318: TM-score 0.41, RMSD 4.03 Å
- 7AEA chain Q against the predicted model O15318: TM-score 0.38, RMSD 3.42 Å
- 7AEA chain Q against the predicted model O15318: TM-score 0.38, RMSD 3.42 Å
- 7AE3 chain Q against the predicted model O15318: TM-score 0.38, RMSD 3.46 Å
Elsewhere
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