UniProt O15263
Beta-defensin 4A (O15263)
Beta-defensin 4A (UniProt O15263): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15263
- Protein
- Beta-defensin 4A
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
11 records of O15263 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E4Q | Solution structure of the human defensin hBD-2 | solution nmr | A | — | — |
| 1E4Q | Solution structure of the human defensin hbd-2 | solution nmr | A | — | — |
| 1FD3 | Human beta-defensin 2 | x-ray diffraction | A, B, C, D | — | — |
| 1FD3 | Human beta-defensin 2 | x-ray diffraction | A, B, C, D | — | — |
| 1FD4 | Human beta-defensin 2 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 1FD4 | Human beta-defensin 2 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 1FQQ | Solution structure of human beta-defensin-2 | solution nmr | A | — | — |
| 1FQQ | Solution structure of human beta-defensin-2 | solution nmr | A | — | — |
| 6CS9 | Crystal structure of human beta-defensin 2 in complex with PIP2 | x-ray diffraction | A, B | PIO | 2 (best 0.36) |
| 6CS9 | Crystal structure of human beta-defensin 2 in complex with PIP2 | x-ray diffraction | A, B | PIO | — |
| O15263 | AlphaFold monomer V2.0 prediction for beta-defensin 4A (O15263) | predicted | A | — | — |
Ligands
- PIO · [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2, 3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate · in 2 records
Experiment against prediction
- 6CS9 chain A against the predicted model O15263: TM-score 0.95, RMSD 0.48 Å
- 6CS9 chain A against the predicted model O15263: TM-score 0.95, RMSD 0.48 Å
- 6CS9 chain B against the predicted model O15263: TM-score 0.94, RMSD 0.48 Å
- 6CS9 chain B against the predicted model O15263: TM-score 0.94, RMSD 0.48 Å
- 1FD4 chain J against the predicted model O15263: TM-score 0.93, RMSD 0.54 Å
- 1FD4 chain J against the predicted model O15263: TM-score 0.93, RMSD 0.54 Å
- 1FD3 chain C against the predicted model O15263: TM-score 0.93, RMSD 0.57 Å
- 1FD3 chain C against the predicted model O15263: TM-score 0.93, RMSD 0.57 Å
- 1FD3 chain D against the predicted model O15263: TM-score 0.93, RMSD 0.56 Å
- 1FD3 chain D against the predicted model O15263: TM-score 0.93, RMSD 0.56 Å
Elsewhere
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