UniProt O15211
Ral guanine nucleotide dissociation stimulator-like 2 (O15211)
Ral guanine nucleotide dissociation stimulator-like 2 (UniProt O15211): 2 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15211
- Protein
- Ral guanine nucleotide dissociation stimulator-like 2
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 13 · 2 records with a druggable one
Structures
3 records of O15211 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8AU4 | Structural insights reveal a heterotetramer between oncogenic K-Ras4BG12V and Rgl2, a RalA/B… | solution nmr | A | — | — |
| 8B69 | Heterotetramer of K-Ras4B(G12V) and Rgl2(RBD) | x-ray diffraction | A, C | — | 6 (best 0.84) |
| O15211 | AlphaFold monomer V2.0 prediction for ral guanine nucleotide dissociation stimulator-like 2 (O15211) | predicted | A | — | 7 (best 0.77) |
Experiment against prediction
- 8B69 chain C against the predicted model O15211: TM-score 0.91, RMSD 1.56 Å
- 8B69 chain A against the predicted model O15211: TM-score 0.87, RMSD 1.81 Å
- 8AU4 chain A against the predicted model O15211: TM-score 0.81, RMSD 2.11 Å
Elsewhere
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