UniProt O15144
Actin-related protein 2/3 complex subunit 2 (O15144)
Actin-related protein 2/3 complex subunit 2 (UniProt O15144): 7 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15144
- Protein
- Actin-related protein 2/3 complex subunit 2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 19 · 4 records with a druggable one
Structures
8 records of O15144 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6UHC | CryoEM structure of human Arp2/3 complex with bound NPFs | electron microscopy | D | — | 5 (best 0.73) |
| 6UHC | Cryoem structure of human ARP2/3 complex with bound npfs | electron microscopy | D | — | — |
| 6YW6 | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | electron microscopy | D | — | 5 (best 0.78) |
| 6YW6 | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | electron microscopy | D | — | — |
| 6YW7 | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | electron microscopy | D | — | 5 (best 0.67) |
| 6YW7 | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | electron microscopy | D | — | — |
| 8P94 | Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches | electron microscopy | D | — | 4 (best 0.81) |
| O15144 | AlphaFold monomer V2.0 prediction for actin-related protein 2/3 complex subunit 2 (O15144) | predicted | A | — | — |
Experiment against prediction
- 6UHC chain D against the predicted model O15144: TM-score 0.99, RMSD 0.75 Å
- 6UHC chain D against the predicted model O15144: TM-score 0.99, RMSD 0.75 Å
- 6YW6 chain D against the predicted model O15144: TM-score 0.98, RMSD 0.93 Å
- 6YW6 chain D against the predicted model O15144: TM-score 0.98, RMSD 0.93 Å
- 6YW7 chain D against the predicted model O15144: TM-score 0.97, RMSD 1.18 Å
- 6YW7 chain D against the predicted model O15144: TM-score 0.97, RMSD 1.18 Å
- 8P94 chain D against the predicted model O15144: TM-score 0.89, RMSD 2.14 Å
Elsewhere
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