UniProt O15119
T-box transcription factor TBX3 (O15119)
T-box transcription factor TBX3 (UniProt O15119): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15119
- Protein
- T-box transcription factor TBX3
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
3 records of O15119 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H6F | Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic… | x-ray diffraction | A, B | MG | 5 (best 0.63) |
| 1H6F | Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic… | x-ray diffraction | A, B | — | — |
| O15119 | AlphaFold monomer V2.0 prediction for T-box transcription factor TBX3 (O15119) | predicted | A | — | 3 (best 0.40) |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 1H6F chain B against the predicted model O15119: TM-score 0.99, RMSD 0.53 Å
- 1H6F chain B against the predicted model O15119: TM-score 0.99, RMSD 0.53 Å
- 1H6F chain A against the predicted model O15119: TM-score 0.97, RMSD 0.89 Å
- 1H6F chain A against the predicted model O15119: TM-score 0.97, RMSD 0.89 Å
Elsewhere
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