UniProt O15020
Spectrin beta chain, non-erythrocytic 2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (UniProt O15020): 6 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15020
- Protein
- Spectrin beta chain, non-erythrocytic 2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 6 · 0 records with a druggable one
Structures
7 records of O15020 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WJM | Solution structure of pleckstrin homology domain of human beta III spectrin. | solution nmr | A | — | — |
| 1WJM | Solution structure of pleckstrin homology domain of human beta III spectrin. | solution nmr | A | — | — |
| 1WYQ | Solution structure of the second CH domain of human spectrin beta chain, brain 2 | solution nmr | A | — | — |
| 1WYQ | Solution structure of the second ch domain of human spectrin beta chain, brain 2 | solution nmr | A | — | — |
| 6ANU | Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain | electron microscopy | f, a, b, c, d, e | — | — |
| 6ANU | Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain | electron microscopy | f, a, b, c, d, e | — | — |
| O15020 | AlphaFold monomer V2.0 prediction for spectrin beta chain, non- erythrocytic 2 (O15020) | predicted | A | — | 6 (best 0.46) |
Experiment against prediction
- 1WJM chain A against the predicted model O15020: TM-score 0.88, RMSD 1.78 Å
- 1WJM chain A against the predicted model O15020: TM-score 0.88, RMSD 1.78 Å
- 6ANU chain f against the predicted model O15020: TM-score 0.84, RMSD 1.98 Å
- 6ANU chain f against the predicted model O15020: TM-score 0.84, RMSD 1.98 Å
- 1WYQ chain A against the predicted model O15020: TM-score 0.82, RMSD 1.88 Å
- 1WYQ chain A against the predicted model O15020: TM-score 0.82, RMSD 1.88 Å
Elsewhere
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