UniProt O14949
Cytochrome b-c1 complex subunit 8 (O14949)
Cytochrome b-c1 complex subunit 8 (UniProt O14949): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14949
- Protein
- Cytochrome b-c1 complex subunit 8
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 1 record with a druggable one
Structures
4 records of O14949 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTE | Cryo-EM structure of human respiratory complex III (cytochrome BC1 complex) | electron microscopy | A, N | CDL, PEE | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | AA, AN | PLX, CDL, PEE | — |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | AA, AN | CDL, PEE, PLX | 1 (best 0.85) |
| O14949 | AlphaFold monomer V2.0 prediction for cytochrome B-C1 complex subunit 8 (O14949) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5XTH chain AN against the predicted model O14949: TM-score 0.88, RMSD 1.12 Å
- 5XTI chain AN against the predicted model O14949: TM-score 0.88, RMSD 1.12 Å
- 5XTI chain AA against the predicted model O14949: TM-score 0.88, RMSD 1.22 Å
- 5XTH chain AA against the predicted model O14949: TM-score 0.88, RMSD 1.22 Å
- 5XTE chain A against the predicted model O14949: TM-score 0.88, RMSD 1.22 Å
Elsewhere
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