UniProt O14929
Histone acetyltransferase type B catalytic subunit (O14929)
Histone acetyltransferase type B catalytic subunit (UniProt O14929), EC 2.3.1.48: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against…
- UniProt
- O14929
- Protein
- Histone acetyltransferase type B catalytic subunit
- EC
- 2.3.1.48
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 1 record with a druggable one
Structures
5 records of O14929 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2P0W | Human histone acetyltransferase 1 (HAT1) | x-ray diffraction | A, B | — | — |
| 2P0W | Human histone acetyltransferase 1 (HAT1) | x-ray diffraction | A, B | — | — |
| 6VO5 | Crystal structure of Human histone acetytransferas 1 (HAT1) in complex with isobutryl-COA and K12A… | x-ray diffraction | A, B | CO6, SO4, UNX | 7 (best 0.62) |
| 6VO5 | Crystal structure of human histone acetytransferas 1 (HAT1) in complex with isobutryl-CoA and K12A… | x-ray diffraction | A, B | CO6, SO4, UNX | — |
| O14929 | AlphaFold monomer V2.0 prediction for histone acetyltransferase type B catalytic subunit (O14929) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2P0W chain A against the predicted model O14929: TM-score 1.00, RMSD 0.33 Å
- 2P0W chain A against the predicted model O14929: TM-score 1.00, RMSD 0.33 Å
- 6VO5 chain A against the predicted model O14929: TM-score 1.00, RMSD 0.47 Å
- 6VO5 chain A against the predicted model O14929: TM-score 1.00, RMSD 0.47 Å
- 6VO5 chain B against the predicted model O14929: TM-score 0.99, RMSD 0.86 Å
- 6VO5 chain B against the predicted model O14929: TM-score 0.99, RMSD 0.86 Å
- 2P0W chain B against the predicted model O14929: TM-score 0.99, RMSD 0.88 Å
- 2P0W chain B against the predicted model O14929: TM-score 0.99, RMSD 0.88 Å
Elsewhere
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