UniProt O14893
Gem-associated protein 2 (O14893)
Gem-associated protein 2 (UniProt O14893): 13 experimental structures and 1 predicted model on GenesisL1, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14893
- Protein
- Gem-associated protein 2
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 31 · 5 records with a druggable one
Structures
14 records of O14893 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LEH | Solution structure of the core SMN-Gemin2 complex | solution nmr | A | — | — |
| 2LEH | Solution structure of the core smn-GEMIN2 complex | solution nmr | A | — | — |
| 5XJL | Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1/D2/F/E/G from… | x-ray diffraction | 2 | — | 5 (best 0.59) |
| 5XJL | Crystal structure of the GEMIN2-binding domain of smn, GEMIN2 in complex with SMD1/D2/F/E/G from… | x-ray diffraction | 2 | — | — |
| 5XJQ | Crystal structure of the GEMIN2-binding domain of smn, GEMIN2 in complex with SMD1(1-82)/D2/F/E/G… | x-ray diffraction | 2 | — | — |
| 5XJR | Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with… | x-ray diffraction | 2 | — | 5 (best 0.58) |
| 5XJR | Crystal structure of the GEMIN2-binding domain of smn, GEMIN2DN39 in complex with… | x-ray diffraction | 2 | — | — |
| 5XJS | Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E… | x-ray diffraction | 2 | — | 7 (best 0.58) |
| 5XJS | Crystal structure of the GEMIN2-binding domain of smn, GEMIN2DN39 in complex with SMD1(1-82)/D2/F/E… | x-ray diffraction | 2 | — | — |
| 5XJT | Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with… | x-ray diffraction | 2 | — | 8 (best 0.57) |
| 5XJT | Crystal structure of the GEMIN2-binding domain of smn, GEMIN2 in complex with… | x-ray diffraction | 2 | — | — |
| 5XJU | Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with… | x-ray diffraction | 2 | — | 6 (best 0.61) |
| 5XJU | Crystal structure of the GEMIN2-binding domain of smn, GEMIN2DN39 in complex with… | x-ray diffraction | 2 | — | — |
| O14893 | AlphaFold monomer V2.0 prediction for gem-associated protein 2 (O14893) | predicted | A | — | — |
Experiment against prediction
- 5XJT chain 2 against the predicted model O14893: TM-score 0.95, RMSD 1.59 Å
- 5XJT chain 2 against the predicted model O14893: TM-score 0.95, RMSD 1.59 Å
- 5XJR chain 2 against the predicted model O14893: TM-score 0.95, RMSD 1.29 Å
- 5XJR chain 2 against the predicted model O14893: TM-score 0.95, RMSD 1.29 Å
- 5XJQ chain 2 against the predicted model O14893: TM-score 0.95, RMSD 1.31 Å
- 5XJU chain 2 against the predicted model O14893: TM-score 0.94, RMSD 1.44 Å
- 5XJU chain 2 against the predicted model O14893: TM-score 0.94, RMSD 1.44 Å
- 5XJS chain 2 against the predicted model O14893: TM-score 0.94, RMSD 1.42 Å
- 5XJS chain 2 against the predicted model O14893: TM-score 0.94, RMSD 1.42 Å
- 5XJL chain 2 against the predicted model O14893: TM-score 0.93, RMSD 1.87 Å
Elsewhere
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