UniProt O14646
O14646
O14646 (UniProt O14646): 20 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14646
- Experimental structures
- 20
- Predicted models
- 1
Structures
21 records of O14646 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B2T | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and… | x-ray diffraction | A, B, C | — | — |
| 2B2T | Tandem chromodomains of human CHD1 complexed with histone H3 tail containing trimethyllysine 4 and… | x-ray diffraction | A, B, C | — | — |
| 2B2U | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and… | x-ray diffraction | A, B, C | — | — |
| 2B2U | Tandem chromodomains of human CHD1 complexed with histone H3 tail containing trimethyllysine 4 and… | x-ray diffraction | A, B, C | — | — |
| 2B2V | Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4 | x-ray diffraction | A, B, C | — | — |
| 2B2V | Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MEK4 | x-ray diffraction | A, B, C | — | — |
| 2B2W | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 | x-ray diffraction | A, B, C | — | — |
| 2B2W | Tandem chromodomains of human CHD1 complexed with histone H3 tail containing trimethyllysine 4 | x-ray diffraction | A, B, C | — | — |
| 2B2Y | Tandem chromodomains of human CHD1 | x-ray diffraction | A, B, C | — | — |
| 2B2Y | Tandem chromodomains of human CHD1 | x-ray diffraction | A, B, C | — | — |
| 2N39 | NMR solution structure of a C-terminal domain of the chromodomain helicase DNA-binding protein 1 | solution nmr | A | — | — |
| 2N39 | NMR solution structure of a C-terminal domain of the chromodomain helicase DNA-binding protein 1 | solution nmr | A | — | — |
| 4B4C | Crystal structure of the DNA-binding domain of human CHD1. | x-ray diffraction | A | — | — |
| 4B4C | Crystal structure of the DNA-binding domain of human CHD1. | x-ray diffraction | A | — | — |
| 4NW2 | Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail… | x-ray diffraction | A, C | — | — |
| 4NW2 | Tandem chromodomains of human CHD1 in complex with influenza virus NS1 C-terminal tail… | x-ray diffraction | A, C | — | — |
| 4O42 | Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at… | x-ray diffraction | A | — | — |
| 4O42 | Tandem chromodomains of human CHD1 in complex with influenza NS1 C- terminal tail dimethylated at… | x-ray diffraction | A | — | — |
| 5AFW | Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation | x-ray diffraction | A | — | — |
| 5AFW | Assembly of methylated LSD1 and CHD1 drives ar-dependent transcription and translocation | x-ray diffraction | A | — | — |
| O14646 | AlphaFold monomer V2.0 prediction for chromodomain-helicase-DNA- binding protein 1 (O14646) | predicted | A | — | — |
Experiment against prediction
- 4NW2 chain C against the predicted model O14646: TM-score 0.96, RMSD 0.98 Å
- 4NW2 chain C against the predicted model O14646: TM-score 0.96, RMSD 0.98 Å
- 4NW2 chain A against the predicted model O14646: TM-score 0.96, RMSD 1.01 Å
- 4NW2 chain A against the predicted model O14646: TM-score 0.96, RMSD 1.01 Å
- 5AFW chain A against the predicted model O14646: TM-score 0.96, RMSD 0.99 Å
- 5AFW chain A against the predicted model O14646: TM-score 0.96, RMSD 0.99 Å
- 4O42 chain A against the predicted model O14646: TM-score 0.96, RMSD 1.03 Å
- 4O42 chain A against the predicted model O14646: TM-score 0.96, RMSD 1.03 Å
- 2B2Y chain B against the predicted model O14646: TM-score 0.96, RMSD 1.01 Å
- 2B2Y chain B against the predicted model O14646: TM-score 0.96, RMSD 1.01 Å
Elsewhere
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