UniProt O14241
Actin-related protein 2/3 complex subunit 2 (O14241)
Actin-related protein 2/3 complex subunit 2 (UniProt O14241): 8 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14241
- Protein
- Actin-related protein 2/3 complex subunit 2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 16 · 4 records with a druggable one
Structures
9 records of O14241 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DWL | Crystal Structure of Fission Yeast Arp2/3 Complex Lacking the Arp2 Subunit | x-ray diffraction | D, I | — | — |
| 3DWL | Crystal structure of fission yeast ARP2/3 complex lacking the ARP2 subunit | x-ray diffraction | D, I | — | — |
| 6W17 | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | electron microscopy | D | — | 2 (best 0.84) |
| 6W17 | Structure of DIP1-activated ARP2/3 complex with nucleated actin filament | electron microscopy | D | — | — |
| 6W18 | Structure of S. pombe ARP2/3 complex in inactive state | electron microscopy | D | — | — |
| 8E9B | Cryo-EM structure of S. pombe Arp2/3 complex in the branch junction | electron microscopy | D | — | 5 (best 0.78) |
| 8UXW | Arp2/3 branch junction complex, ADP state | electron microscopy | D | — | 4 (best 0.83) |
| 8UXX | Arp2/3 branch junction complex, BeFx state | electron microscopy | D | — | 5 (best 0.85) |
| O14241 | AlphaFold monomer V2.0 prediction for actin-related protein 2/3 complex subunit 2 (O14241) | predicted | A | — | — |
Experiment against prediction
- 3DWL chain D against the predicted model O14241: TM-score 0.98, RMSD 1.05 Å
- 3DWL chain D against the predicted model O14241: TM-score 0.98, RMSD 1.05 Å
- 3DWL chain I against the predicted model O14241: TM-score 0.98, RMSD 1.05 Å
- 3DWL chain I against the predicted model O14241: TM-score 0.98, RMSD 1.05 Å
- 6W18 chain D against the predicted model O14241: TM-score 0.95, RMSD 1.52 Å
- 6W17 chain D against the predicted model O14241: TM-score 0.94, RMSD 1.69 Å
- 6W17 chain D against the predicted model O14241: TM-score 0.94, RMSD 1.69 Å
- 8UXX chain D against the predicted model O14241: TM-score 0.91, RMSD 1.95 Å
- 8UXW chain D against the predicted model O14241: TM-score 0.91, RMSD 1.98 Å
- 8E9B chain D against the predicted model O14241: TM-score 0.90, RMSD 2.04 Å
Elsewhere
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