UniProt O13877
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (O13877)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (UniProt O13877): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O13877
- Protein
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 4 records with a druggable one
Structures
12 records of O13877 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3H0G | RNA Polymerase II from Schizosaccharomyces pombe | x-ray diffraction | J, V | — | — |
| 3H0G | RNA polymerase II from schizosaccharomyces pombe | x-ray diffraction | J, V | — | — |
| 5U0S | Cryo-EM structure of the Mediator-RNAPII complex | electron microscopy | j | — | — |
| 5U0S | Cryo-EM structure of the mediator-rnapii complex | electron microscopy | j | — | — |
| 7AOC | Schizosaccharomyces pombe RNA polymerase I (monomer) | electron microscopy | J | ZN | 5 (best 0.80) |
| 7AOC | Schizosaccharomyces pombe RNA polymerase I (monomer) | electron microscopy | J | ZN | — |
| 7AOD | Schizosaccharomyces pombe RNA polymerase I (dimer) | electron microscopy | J, V | ZN | 4 (best 0.84) |
| 7AOD | Schizosaccharomyces pombe RNA polymerase I (dimer) | electron microscopy | J, V | ZN | — |
| 7AOE | Schizosaccharomyces pombe RNA polymerase I (elongation complex) | electron microscopy | J | ZN | 3 (best 0.78) |
| 7AOE | Schizosaccharomyces pombe RNA polymerase I (elongation complex) | electron microscopy | J | ZN | — |
| 8QSZ | Structure of s. pombe RNA polymerase II in complex with DSIF and Rat1/Rai1 | electron microscopy | J | — | 2 (best 0.79) |
| O13877 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC5… | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 8QSZ chain J against the predicted model O13877: TM-score 0.93, RMSD 1.18 Å
- 5U0S chain j against the predicted model O13877: TM-score 0.90, RMSD 0.92 Å
- 5U0S chain j against the predicted model O13877: TM-score 0.90, RMSD 0.92 Å
- 3H0G chain J against the predicted model O13877: TM-score 0.90, RMSD 0.92 Å
- 3H0G chain J against the predicted model O13877: TM-score 0.90, RMSD 0.92 Å
- 7AOC chain J against the predicted model O13877: TM-score 0.87, RMSD 1.31 Å
- 7AOC chain J against the predicted model O13877: TM-score 0.87, RMSD 1.31 Å
- 7AOE chain J against the predicted model O13877: TM-score 0.86, RMSD 1.29 Å
- 7AOE chain J against the predicted model O13877: TM-score 0.86, RMSD 1.29 Å
- 7AOD chain J against the predicted model O13877: TM-score 0.86, RMSD 1.38 Å
Elsewhere
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