UniProt O08665
Semaphorin-3A (O08665)
Semaphorin-3A (UniProt O08665): 8 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O08665
- Protein
- Semaphorin-3A
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 23 · 2 records with a druggable one
Structures
9 records of O08665 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Q47 | Structure of the Semaphorin 3A Receptor-Binding Module | x-ray diffraction | A, B | — | — |
| 1Q47 | Structure of the semaphorin 3A receptor-binding module | x-ray diffraction | A, B | — | — |
| 4GZ8 | Mouse Semaphorin 3A, domains Sema-PSI-IG | x-ray diffraction | A, B | — | — |
| 4GZ8 | Mouse semaphorin 3A, domains sema-psi-ig | x-ray diffraction | A, B | — | — |
| 4GZA | Complex of mouse Plexin A2 - Semaphorin 3A - Neuropilin-1 | x-ray diffraction | G | — | — |
| 4GZA | Complex of mouse plexin A2 - semaphorin 3A - neuropilin-1 | x-ray diffraction | G | — | — |
| 7M0R | Cryo-EM structure of the Sema3A/PlexinA4/Neuropilin 1 complex | electron microscopy | C, D | — | 13 (best 0.84) |
| 7M0R | Cryo-EM structure of the SEMA3A/PLEXINA4/NEUROPILIN 1 complex | electron microscopy | C, D | — | — |
| O08665 | AlphaFold monomer V2.0 prediction for semaphorin-3A (O08665) | predicted | A | — | 10 (best 0.73) |
Experiment against prediction
- 4GZA chain G against the predicted model O08665: TM-score 0.99, RMSD 0.92 Å
- 4GZA chain G against the predicted model O08665: TM-score 0.99, RMSD 0.92 Å
- 1Q47 chain A against the predicted model O08665: TM-score 0.99, RMSD 0.92 Å
- 1Q47 chain A against the predicted model O08665: TM-score 0.99, RMSD 0.92 Å
- 4GZ8 chain B against the predicted model O08665: TM-score 0.99, RMSD 1.03 Å
- 4GZ8 chain B against the predicted model O08665: TM-score 0.99, RMSD 1.03 Å
- 4GZ8 chain A against the predicted model O08665: TM-score 0.99, RMSD 1.05 Å
- 4GZ8 chain A against the predicted model O08665: TM-score 0.99, RMSD 1.05 Å
- 1Q47 chain B against the predicted model O08665: TM-score 0.99, RMSD 1.08 Å
- 1Q47 chain B against the predicted model O08665: TM-score 0.99, RMSD 1.08 Å
Elsewhere
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