UniProt O06543
Alpha-methylacyl-CoA racemase (O06543)
Alpha-methylacyl-CoA racemase (UniProt O06543), EC 5.1.99.4: 7 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O06543
- Protein
- Alpha-methylacyl-CoA racemase
- EC
- 5.1.99.4
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 13 · 3 records with a druggable one
Structures
8 records of O06543 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1X74 | Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis- mutational and structural… | x-ray diffraction | A, B, C, D | — | — |
| 1X74 | Alpha-methylacyl-CoA racemase from mycobacterium tuberculosis- mutational and structural… | x-ray diffraction | A, B, C, D | — | — |
| 2YIM | The enolisation chemistry of a thioester-dependent racemase: the 1.4 A crystal structure of a… | x-ray diffraction | A, B, C, D | — | — |
| 2YIM | The enolisation chemistry of a thioester-dependent racemase: the 1.4 a crystal structure of a… | x-ray diffraction | A, B, C, D | — | — |
| 8RP3 | Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (H126A mutant) | x-ray diffraction | A, B | — | 5 (best 0.72) |
| 8RP4 | Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (D156A mutant) | x-ray diffraction | A, B | — | 3 (best 0.70) |
| 8RP5 | Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (E241A mutant) | x-ray diffraction | A, B | — | 5 (best 0.70) |
| O06543 | AlphaFold monomer V2.0 prediction for alpha-methylacyl-CoA racemase (O06543) | predicted | A | — | — |
Experiment against prediction
- 8RP3 chain A against the predicted model O06543: TM-score 0.99, RMSD 0.63 Å
- 8RP5 chain A against the predicted model O06543: TM-score 0.99, RMSD 0.63 Å
- 8RP4 chain A against the predicted model O06543: TM-score 0.99, RMSD 0.65 Å
- 8RP3 chain B against the predicted model O06543: TM-score 0.99, RMSD 0.65 Å
- 8RP5 chain B against the predicted model O06543: TM-score 0.99, RMSD 0.66 Å
- 8RP4 chain B against the predicted model O06543: TM-score 0.99, RMSD 0.67 Å
- 2YIM chain C against the predicted model O06543: TM-score 0.99, RMSD 0.83 Å
- 2YIM chain C against the predicted model O06543: TM-score 0.99, RMSD 0.83 Å
- 1X74 chain A against the predicted model O06543: TM-score 0.99, RMSD 0.84 Å
- 1X74 chain A against the predicted model O06543: TM-score 0.99, RMSD 0.84 Å
Elsewhere
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