UniProt O05207
Type 2 DNA topoisomerase 6 subunit B (O05207)
Type 2 DNA topoisomerase 6 subunit B (UniProt O05207): 16 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O05207
- Protein
- Type 2 DNA topoisomerase 6 subunit B
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
17 records of O05207 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MU5 | Structure of topoisomerase subunit | x-ray diffraction | A | — | — |
| 1MU5 | Structure of topoisomerase subunit | x-ray diffraction | A | — | — |
| 1MX0 | Structure of topoisomerase subunit | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1MX0 | Structure of topoisomerase subunit | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1Z59 | Topoisomerase VI-B, ADP-bound monomer form | x-ray diffraction | A | — | — |
| 1Z59 | Topoisomerase VI-B, ADP-bound monomer form | x-ray diffraction | A | — | — |
| 1Z5A | Topoisomerase VI-B, ADP-bound dimer form | x-ray diffraction | A, B | — | — |
| 1Z5A | Topoisomerase VI-B, ADP-bound dimer form | x-ray diffraction | A, B | — | — |
| 1Z5B | Topoisomerase VI-B, ADP AlF4- bound dimer form | x-ray diffraction | A, B | — | — |
| 1Z5B | Topoisomerase VI-B, ADP ALF4- bound dimer form | x-ray diffraction | A, B | — | — |
| 1Z5C | Topoisomerase VI-B, ADP Pi bound dimer form | x-ray diffraction | A, B | — | — |
| 1Z5C | Topoisomerase VI-B, ADP pi bound dimer form | x-ray diffraction | A, B | — | — |
| 2HKJ | Topoisomerase VI-B bound to radicicol | x-ray diffraction | A | — | — |
| 2HKJ | Topoisomerase VI-B bound to radicicol | x-ray diffraction | A | — | — |
| 2ZBK | Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms | x-ray diffraction | B, D, F, H | — | — |
| 2ZBK | Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms | x-ray diffraction | B, D, F, H | — | — |
| O05207 | AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit B (O05207) | predicted | A | — | 6 (best 0.75) |
Experiment against prediction
- 1MX0 chain F against the predicted model O05207: TM-score 0.98, RMSD 1.07 Å
- 1MX0 chain F against the predicted model O05207: TM-score 0.98, RMSD 1.07 Å
- 1MX0 chain E against the predicted model O05207: TM-score 0.98, RMSD 1.24 Å
- 1MX0 chain E against the predicted model O05207: TM-score 0.98, RMSD 1.24 Å
- 1MX0 chain B against the predicted model O05207: TM-score 0.98, RMSD 1.22 Å
- 1MX0 chain B against the predicted model O05207: TM-score 0.98, RMSD 1.22 Å
- 1MX0 chain A against the predicted model O05207: TM-score 0.98, RMSD 1.24 Å
- 1MX0 chain A against the predicted model O05207: TM-score 0.98, RMSD 1.24 Å
- 1Z5B chain A against the predicted model O05207: TM-score 0.97, RMSD 1.35 Å
- 1Z5B chain A against the predicted model O05207: TM-score 0.97, RMSD 1.35 Å
Elsewhere
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