UniProt O02697
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (O02697)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (UniProt O02697), EC 2.7.1.137, 2.7.1.153: 12 experimental structures on GenesisL1, 16 pockets. Binding sites, pockets, druggability and 3D structures…
- UniProt
- O02697
- Protein
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- EC
- 2.7.1.137, 2.7.1.153, 2.7.1.154, 2.7.11.1
- Experimental structures
- 12
- Predicted models
- 0
- Pockets
- 16 · 1 record with a druggable one
Structures
12 records of O02697 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E7U | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E7U | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E7V | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E7V | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E8W | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E8W | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E8X | Structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling | x-ray diffraction | A | — | — |
| 1E8X | Structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling | x-ray diffraction | A | — | — |
| 1E90 | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 1E90 | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin… | x-ray diffraction | A | — | — |
| 8AJ8 | Structure of p110 gamma bound to the p84 regulatory subunit | x-ray diffraction | A, C, E, G | — | 16 (best 0.83) |
| O02697 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic… | — | — | — |
Elsewhere
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