UniProt O02372
odorant binding protein LUSH (O02372)
odorant binding protein LUSH (UniProt O02372): 24 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O02372
- Protein
- odorant binding protein LUSH
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 26 · 7 records with a druggable one
Structures
25 records of O02372 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OOF | Complex of Drosophila odorant binding protein LUSH with ethanol | x-ray diffraction | A, B | — | 5 (best 0.80) |
| 1OOF | Complex of drosophila odorant binding protein lush with ethanol | x-ray diffraction | A, B | — | — |
| 1OOG | Complex of Drosophila odorant binding protein LUSH with propanol | x-ray diffraction | A, B | — | 5 (best 0.81) |
| 1OOG | Complex of drosophila odorant binding protein lush with propanol | x-ray diffraction | A, B | — | — |
| 1OOH | Complex of Drosophila odorant binding protein LUSH with butanol | x-ray diffraction | A, B | — | 5 (best 0.81) |
| 1OOH | Complex of drosophila odorant binding protein lush with butanol | x-ray diffraction | A, B | — | — |
| 1OOI | Crystal structure of LUSH from Drosophila melanogaster at pH 6.5 | x-ray diffraction | X | — | 1 (best 0.80) |
| 1OOI | Crystal structure of lush from drosophila melanogaster at pH 6.5 | x-ray diffraction | X | — | — |
| 1T14 | Crystal structure of LUSH from Drosophila melanogaster: apo protein | x-ray diffraction | A, B | — | 5 (best 0.81) |
| 1T14 | Crystal structure of lush from drosophila melanogaster: apo protein | x-ray diffraction | A, B | — | — |
| 2GTE | Drosophila OBP LUSH bound to attractant pheromone 11-cis-vaccenyl acetate | x-ray diffraction | A, B | PO4, VA | 4 (best 0.84) |
| 2GTE | Drosophila obp lush bound to attractant pheromone 11-cis- vaccenyl acetate | x-ray diffraction | A, B | — | — |
| 2QDI | Drosophila OBP LUSH D118A mutation | x-ray diffraction | A, B | — | — |
| 2QDI | Drosophila obp lush D118A mutation | x-ray diffraction | A, B | — | — |
| 3B6X | Complex of S52A Substituted Drosophila LUSH protein with Butanol | x-ray diffraction | A, B | — | — |
| 3B6X | Complex of S52A substituted drosophila lush protein with butanol | x-ray diffraction | A, B | — | — |
| 3B7A | Complex of S52A Substituted Droposphila LUSH protein with Ethanol | x-ray diffraction | A, B | — | — |
| 3B7A | Complex of S52A substituted droposphila lush protein with ethanol | x-ray diffraction | A, B | — | — |
| 3B86 | Crystal structure of T57S substituted LUSH protein complexed with ethanol | x-ray diffraction | A, B | — | — |
| 3B86 | Crystal structure of T57S substituted lush protein complexed with ethanol | x-ray diffraction | A, B | — | — |
| 3B87 | Complex of T57A Substituted Droposphila LUSH protein with Butanol | x-ray diffraction | A, B | — | — |
| 3B87 | Complex of T57A substituted droposphila lush protein with butanol | x-ray diffraction | A, B | — | — |
| 3B88 | Complex of T57A Substituted Drosophila LUSH Protein with Ethanol | x-ray diffraction | A, B | — | — |
| 3B88 | Complex of T57A substituted drosophila lush protein with ethanol | x-ray diffraction | A, B | — | — |
| O02372 | AlphaFold monomer V2.0 prediction for general odorant-binding protein lush (O02372) | predicted | A | — | 1 (best 0.82) |
Ligands
Experiment against prediction
- 3B7A chain A against the predicted model O02372: TM-score 1.00, RMSD 0.26 Å
- 3B7A chain A against the predicted model O02372: TM-score 1.00, RMSD 0.26 Å
- 1OOF chain A against the predicted model O02372: TM-score 1.00, RMSD 0.26 Å
- 1OOF chain A against the predicted model O02372: TM-score 1.00, RMSD 0.26 Å
- 1OOG chain A against the predicted model O02372: TM-score 1.00, RMSD 0.27 Å
- 1OOG chain A against the predicted model O02372: TM-score 1.00, RMSD 0.27 Å
- 3B88 chain A against the predicted model O02372: TM-score 1.00, RMSD 0.28 Å
- 3B88 chain A against the predicted model O02372: TM-score 1.00, RMSD 0.28 Å
- 1T14 chain A against the predicted model O02372: TM-score 1.00, RMSD 0.28 Å
- 1T14 chain A against the predicted model O02372: TM-score 1.00, RMSD 0.28 Å
Elsewhere
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